Blue Jays vs Astros Prediction, Odds, Moneyline, Spread & Over/Under for April 23

Odds updated as of 7:11 a.m.

Wednesday's slate in the MLB includes a matchup between the Toronto Blue Jays and the Houston Astros.

Here's everything you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Blue Jays vs Astros Game Info

• Toronto Blue Jays (12-12) vs. Houston Astros (12-11)
• Date: Wednesday, April 23, 2025
• Time: 7:40 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: MLB Network, SCHN2, and SN1

Blue Jays vs Astros Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TOR: (-116) | HOU: (-102)
• Spread: TOR: -1.5 (+146) | HOU: +1.5 (-178)
• Total: 8 -- Over: (-115) | Under: (-105)

Blue Jays vs Astros Probable Starting Pitchers

Probable Pitchers: Bowden Francis (Blue Jays) - 2-2, 3.13 ERA vs Ryan Gusto (Astros) - 2-1, 3.18 ERA

The Blue Jays will give the ball to Bowden Francis (2-2, 3.13 ERA), who is eyeing win No. 3 on the season, and the Astros will counter with Ryan Gusto (2-1, 3.18 ERA). Francis' team has covered the spread in each of the four opportunities this season. Francis' team is 2-0 this season when he starts and they're favored on the moneyline. Gusto has started two games with set spreads, and the Astros went 1-1-0. The Astros have always been the moneyline underdog when Gusto starts this season.

Blue Jays vs Astros Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (57.8%)

Blue Jays vs Astros Moneyline

• The moneyline numbers for Blue Jays vs. Astros reveal Toronto as the favorite (-116) and Houston as the underdog (-102) despite being the home team.

Blue Jays vs Astros Spread

• The Astros are +1.5 on the run line against the Blue Jays. The Astros are -178 to cover, and the Blue Jays are +146.

Blue Jays vs Astros Over/Under

• Blue Jays versus Astros, on April 23, has an over/under of 8, with the over being -115 and the under -105.

Bet on Toronto Blue Jays vs. Houston Astros on FanDuel today!

Blue Jays vs Astros Betting Trends

• The Blue Jays have been chosen as favorites in eight games this year and have walked away with the win five times (62.5%) in those games.
• This year Toronto has won five of eight games when listed as at least -116 on the moneyline.
• The Blue Jays' games have gone over the total in nine of their 24 opportunities.
• The Blue Jays are 16-8-0 against the spread in their 24 games that had a posted line this season.
• The Astros have won five of the nine games they were the underdog on the moneyline this season (55.6%).
• In games it has played as a moneyline underdog with odds of -102 or longer, Houston has a 3-3 record (winning 50% of its games).
• The Astros have played in 23 games with an over/under set, and have combined with their opponents to go over the total eight times (8-13-2).
• The Astros have a 13-10-0 record ATS this season (covering 56.5% of the time).

Blue Jays Player Leaders

• Bo Joseph Bichette has an OPS of .714, fueled by an OBP of .339 and a team-best slugging percentage of .375 this season. He has a .298 batting average.
• Among all qualifying hitters, he ranks 36th in batting average, his on-base percentage ranks 74th, and he is 102nd in slugging.
• Vladimir Guerrero Jr. has six doubles, a home run and 14 walks. He's batting .278 and slugging .378 with an on-base percentage of .377.
• He is 55th in batting average, 33rd in on-base percentage and 100th in slugging in the major leagues.
• George Springer leads his team in OBP (.416) and total hits (22) this season.
• Andres Gimenez has been key for Toronto with 17 hits, an OBP of .275 plus a slugging percentage of .333.

Astros Player Leaders

• Jeremy Pena is batting .253 with three doubles, three home runs and eight walks. He's slugging .398 with an on-base percentage of .330.
• He is 78th in batting average, 83rd in on-base percentage and 96th in slugging percentage among all qualifying hitters in the majors.
• Pena hopes to build on a 13-game hitting streak in this matchup. In his last 10 games he is hitting .324 with two doubles, a home run, three walks and five RBI.
• Isaac Paredes' .340 on-base percentage leads his team. He has a batting average of .233 while slugging .384.
• He is 99th in batting average, 72nd in on-base percentage and 99th in slugging percentage in the big leagues.
• Jose Carlos Altuve has put up a slugging percentage of .415 and has 28 hits, both team-high numbers for the Astros.
• Yordan Ruben Alvarez is batting .213 with three doubles, two home runs and 13 walks.

Blue Jays vs Astros Head to Head

• 4/22/2025: 5-1 HOU (Favorite: Blue Jays, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/21/2025: 7-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/4/2024: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 7/3/2024: 9-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/2/2024: 7-6 TOR (Favorite: Blue Jays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/1/2024: 3-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 4/3/2024: 8-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 4/2/2024: 2-1 TOR (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 4/1/2024: 10-0 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -144, Underdog Moneyline: +122)
• 6/8/2023: 3-2 TOR (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -118, Underdog Moneyline: -100)

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