Bills vs Panthers Prediction, Odds, Picks, Best Bets for NFL Week 8

The NFL schedule on Sunday includes the Buffalo Bills taking on the Carolina Panthers.
Before you place your bet on this game at FanDuel Sportsbook, here are the NFL moneyline insights you need to know.
Bills vs Panthers Prediction & Pick
All NFL win probability predictions and picks are according to numberFire.
Prediction: Bills win (62.6%)
Bills vs Panthers Point Spread
The Bills are 7.5-point favorites against the Panthers. The Bills are -102 to cover the spread, while the Panthers are -120 to cover as a 7.5-point underdog.
Bills vs Panthers Over/Under
The over/under for Bills-Panthers on Oct. 26 is 47.5. The over is -106, and the under is -114.
Bills vs Panthers Moneyline
Buffalo is the favorite, -420 on the moneyline, while Carolina is a +330 underdog despite being at home.
Bills vs Panthers Betting Trends
- Buffalo has two wins against the spread this year.
- The Bills are winless ATS (0-3) when playing as at least 7.5-point favorites this season.
- Out of six Bills games so far this year, three have hit the over.
- The Panthers have five wins in seven contests against the spread this year.
- The Panthers have seen four of their seven games go over the point total.
Check out even more in-depth Bills vs. Panthers analysis on FanDuel Research.
Bills vs Panthers Odds & Spread
- All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: BUF: (-420) | CAR: (+330)
- Spread: BUF: -7.5 (-102) | CAR: +7.5 (-120)
- Total: 47.5 -- Over: (-106) | Under: (-114)
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