Bills vs Jaguars Prediction, Odds, Moneyline, Betting Trends, Spread & Over/Under for NFL Week 5 - October 8

The Buffalo Bills versus the Jacksonville Jaguars is on the NFL schedule for Sunday.

Get the latest NFL odds ahead of this game on FanDuel Sportsbook.

Bills vs Jaguars Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Bills win (67.8%)

Bills vs Jaguars Point Spread

The Bills are 5.5-point favorites against the Jaguars. The Bills are -110 to cover the spread, while the Jaguars are -110 to cover as a 5.5-point underdog.

Bills vs Jaguars Over/Under

The over/under for the Bills versus Jaguars game on October 8 has been set at 48.5, with -105 odds on the over and -115 odds on the under.

Bills vs Jaguars Moneyline

Buffalo is a -260 favorite on the moneyline, while Jacksonville is a +215 underdog on the road.

Bills vs Jaguars Betting Trends

• Buffalo's record against the spread is 3-1-0.
• The Bills have covered every time (2-0) as a 5.5-point favorite or greater this year.
• Two of the Bills' four games have gone over the point total.
• The Jaguars have posted two wins against the spread this year.
• Two Jaguars games (out of four) have hit the over this season.

Bills vs Jaguars Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BUF: (-260) | JAX: (+215)
• Spread: BUF: -5.5 (-110) | JAX: +5.5 (-110)
• Total: 48.5 -- Over: (-105) | Under: (-115)

Kick off the NFL season with $200 in Bonus Bets - win or lose - when you place your first $5 bet!