Bills vs Chargers Week 16 NFL Odds, Predictions, Spread, Kickoff Time & Best Bets for December 23

The Buffalo Bills versus the Los Angeles Chargers is on the NFL schedule for Saturday.

We've got you covered, in terms of the vital information regarding NFL betting lines, before you make your wager on FanDuel Sportsbook.

Bills vs Chargers Prediction & Pick

All NFL win probability predictions and picks are according to numberFire.
Prediction: Bills win (71.8%)

Bills vs Chargers Point Spread

The Bills are 12.5-point favorites against the Chargers. The Bills are -108 to cover the spread, while the Chargers are -112 to cover as a 12.5-point underdog.

Bills vs Chargers Over/Under

An over/under of 44.5 has been set for Bills-Chargers on December 23, with the over being -108 and the under -112.

Bills vs Chargers Moneyline

Los Angeles is the underdog, +480 on the moneyline, while Buffalo is a -650 favorite despite being on the road.

Bills vs Chargers Betting Trends

• Buffalo's record against the spread is 6-8-0.
• The Bills don't have a win ATS (0-1) as a 12.5-point favorite or greater this year.
• There have been four Bills games (out of 14) that went over the total this season.
• The Chargers are 5-9-0 against the spread this season.
• The Chargers have seen four of their 14 games go over the point total.

Bills vs Chargers Odds & Spread

• All NFL odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BUF: (-650) | LAC: (+480)
• Spread: BUF: -12.5 (-108) | LAC: +12.5 (-112)
• Total: 44.5 -- Over: (-108) | Under: (-112)

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