Best College Football Games Week 6: Predictions, Odds, Picks, Best Bets

The Week 6 college football slate includes 17 games with a ranked team in play. Among those games is the No. 1 Alabama Crimson Tide taking on the Vanderbilt Commodores.

Before this weekend's college football games, here's an in-depth look at the odds.

Oregon vs. Michigan State

• Matchup: Michigan State Spartans at No. 6 Oregon Ducks
• Projected Favorite: Oregon (95.45% win probability)
• Spread: Oregon (-23.5)
• Total: 52.5
• Time: 9:00 PM ET
• Date: Oct. 4
• TV Channel: FOX

Bet on Oregon vs. Michigan State with FanDuel Sportsbook.

UNLV vs. Syracuse

• Matchup: Syracuse Orange at No. 25 UNLV Rebels
• Projected Favorite: UNLV (85.80% win probability)
• Spread: UNLV (-6.5)
• Total: 58.5
• Time: 9:00 PM ET
• Date: Oct. 4
• TV Channel: Fox Sports 1

Bet on UNLV vs. Syracuse with FanDuel Sportsbook.

Penn State vs. UCLA

• Matchup: UCLA Bruins at No. 7 Penn State Nittany Lions
• Projected Favorite: Penn State (89.67% win probability)
• Spread: Penn State (-26.5)
• Total: 46.5
• Time: 12:00 PM ET
• Date: Oct. 5
• TV Channel: FOX

Bet on Penn State vs. UCLA with FanDuel Sportsbook.

Louisville vs. SMU

• Matchup: SMU Mustangs at No. 22 Louisville Cardinals
• Projected Favorite: Louisville (74.09% win probability)
• Spread: Louisville (-6.5)
• Total: 56.5
• Time: 12:00 PM ET
• Date: Oct. 5
• TV Channel: ESPN

Bet on Louisville vs. SMU with FanDuel Sportsbook.

Texas A&M vs. Missouri

• Matchup: No. 9 Missouri Tigers at Texas A&M Aggies
• Projected Favorite: Missouri (50.36% win probability)
• Spread: Texas A&M (-2.5)
• Total: 48.5
• Time: 12:00 PM ET
• Date: Oct. 5
• TV Channel: ABC

Bet on Texas A&M vs. Missouri with FanDuel Sportsbook.

Ohio State vs. Iowa

• Matchup: Iowa Hawkeyes at No. 3 Ohio State Buckeyes
• Projected Favorite: Ohio State (86.85% win probability)
• Spread: Ohio State (-19.5)
• Total: 45.5
• Time: 3:30 PM ET
• Date: Oct. 5
• TV Channel: CBS

Bet on Ohio State vs. Iowa with FanDuel Sportsbook.

Northwestern vs. Indiana

• Matchup: No. 23 Indiana Hoosiers at Northwestern Wildcats
• Projected Favorite: Indiana (69.39% win probability)
• Spread: Indiana (-13.5)
• Total: 41.5
• Time: 3:30 PM ET
• Date: Oct. 5
• TV Channel: BTN

Bet on Northwestern vs. Indiana with FanDuel Sportsbook.

Georgia vs. Auburn

• Matchup: Auburn Tigers at No. 5 Georgia Bulldogs
• Projected Favorite: Georgia (90.93% win probability)
• Spread: Georgia (-24.5)
• Total: 52.5
• Time: 3:30 PM ET
• Date: Oct. 5
• TV Channel: ABC

Bet on Georgia vs. Auburn with FanDuel Sportsbook.

South Carolina vs. Ole Miss

• Matchup: No. 12 Ole Miss Rebels at South Carolina Gamecocks
• Projected Favorite: Ole Miss (73.80% win probability)
• Spread: Ole Miss (-9.5)
• Total: 53.5
• Time: 3:30 PM ET
• Date: Oct. 5
• TV Channel: ESPN

Bet on South Carolina vs. Ole Miss with FanDuel Sportsbook.

Vanderbilt vs. Alabama

• Matchup: No. 1 Alabama Crimson Tide at Vanderbilt Commodores
• Projected Favorite: Alabama (93.28% win probability)
• Spread: Alabama (-22.5)
• Total: 55.5
• Time: 4:15 PM ET
• Date: Oct. 5
• TV Channel: SEC Network

Bet on Vanderbilt vs. Alabama with FanDuel Sportsbook.

Boise State vs. Utah State

• Matchup: Utah State Aggies at No. 21 Boise State Broncos
• Projected Favorite: Boise State (96.80% win probability)
• Spread: Boise State (-26.5)
• Total: 66.5
• Time: 7:00 PM ET
• Date: Oct. 5
• TV Channel: Fox Sports 2

Bet on Boise State vs. Utah State with FanDuel Sportsbook.

Florida State vs. Clemson

• Matchup: No. 15 Clemson Tigers at Florida State Seminoles
• Projected Favorite: Clemson (67.92% win probability)
• Spread: Clemson (-14.5)
• Total: 47.5
• Time: 7:00 PM ET
• Date: Oct. 5
• TV Channel: ESPN

Bet on Florida State vs. Clemson with FanDuel Sportsbook.

Arkansas vs. Tennessee

• Matchup: No. 4 Tennessee Volunteers at Arkansas Razorbacks
• Projected Favorite: Tennessee (90.31% win probability)
• Spread: Tennessee (-13.5)
• Total: 58.5
• Time: 7:30 PM ET
• Date: Oct. 5
• TV Channel: ABC

Bet on Arkansas vs. Tennessee with FanDuel Sportsbook.

Iowa State vs. Baylor

• Matchup: Baylor Bears at No. 16 Iowa State Cyclones
• Projected Favorite: Iowa State (85.36% win probability)
• Spread: Iowa State (-11.5)
• Total: 44.5
• Time: 7:30 PM ET
• Date: Oct. 5
• TV Channel: FOX

Bet on Iowa State vs. Baylor with FanDuel Sportsbook.

Minnesota vs. USC

• Matchup: No. 11 USC Trojans at Minnesota Golden Gophers
• Projected Favorite: USC (68.25% win probability)
• Spread: USC (-8.5)
• Total: 50.5
• Time: 7:30 PM ET
• Date: Oct. 5
• TV Channel: BTN

Bet on Minnesota vs. USC with FanDuel Sportsbook.

Washington vs. Michigan

• Matchup: No. 10 Michigan Wolverines at Washington Huskies
• Projected Favorite: Washington (64.85% win probability)
• Spread: Washington (-2.5)
• Total: 41.5
• Time: 7:30 PM ET
• Date: Oct. 5
• TV Channel: NBC

Bet on Washington vs. Michigan with FanDuel Sportsbook.

California vs. Miami (FL)

• Matchup: No. 8 Miami (FL) Hurricanes at California Golden Bears
• Projected Favorite: Miami (FL) (82.81% win probability)
• Spread: Miami (FL) (-10.5)
• Total: 54.5
• Time: 10:30 PM ET
• Date: Oct. 5
• TV Channel: ESPN

Bet on California vs. Miami (FL) with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

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