Astros vs Reds Prediction, Odds, Moneyline, Spread & Over/Under for May 9

Odds updated as of 9:12 a.m.

The MLB's Friday slate includes the Houston Astros facing the Cincinnati Reds.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Reds Game Info

• Houston Astros (18-18) vs. Cincinnati Reds (19-20)
• Date: Friday, May 9, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and FDSOH

Astros vs Reds Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-178) | CIN: (+150)
• Spread: HOU: -1.5 (+122) | CIN: +1.5 (-146)
• Total: 7.5 -- Over: (-118) | Under: (-104)

Astros vs Reds Probable Starting Pitchers

Probable Pitchers: Hunter Brown (Astros) - 5-1, 1.67 ERA vs Nicholas Martínez (Reds) - 1-3, 4.19 ERA

The Astros will give the nod to Hunter Brown (5-1, 1.67 ERA), who is eyeing win No. 6 on the season, and the Reds will turn to Nicholas Martinez (1-3, 4.19 ERA). Brown's team is 5-2-0 against the spread this season in his starts. Brown's team has a record of 4-2 this season when he starts and they are the favorite on the moneyline. The Reds have gone 2-5-0 against the spread when Martinez starts. The Reds were the moneyline underdog for four Martinez starts this season -- they lost each time.

Astros vs Reds Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (59%)

Astros vs Reds Moneyline

• Houston is a -178 favorite on the moneyline, while Cincinnati is a +150 underdog on the road.

Astros vs Reds Spread

• The Astros are hosting the Reds and are favored by 1.5 runs on the spread. The Astros are +122 to cover the runline, with the Reds being -146.

Astros vs Reds Over/Under

• Astros versus Reds, on May 9, has an over/under of 7.5, with the over being -118 and the under -104.

Bet on Houston Astros vs. Cincinnati Reds on FanDuel today!

Astros vs Reds Betting Trends

• The Astros have come away with 13 wins in the 25 contests they have been listed as the favorites in this season.
• Houston has been listed as a favorite of -178 or more on two occasions this season and split those games.
• The Astros' games have gone over the total in 16 of their 36 opportunities.
• The Astros are 20-16-0 against the spread in their 36 games with a line set by sportsbooks this season.
• The Reds have been the underdog on the moneyline 21 total times this season. They've finished 9-12 in those games.
• Cincinnati is 1-2 (winning just 33.3% of its games) when playing as a moneyline underdog of +150 or longer.
• In the 38 games oddsmakers have set an over/under for the Reds, they have combined with opponents to go over the total 17 times (17-20-1).
• The Reds have covered 52.6% of their games this season, going 20-18-0 ATS.

Astros Player Leaders

• Jeremy Pena leads Houston in slugging percentage (.434) and total hits (38) this season. He's batting .279 with an on-base percentage of .340.
• Among qualified hitters in the majors, he ranks 42nd in batting average, 64th in on-base percentage, and 59th in slugging.
• Isaac Paredes has 33 hits this season and a team-best OBP of .368. He's batting .256 and slugging .388.
• He ranks 68th in batting average, 38th in on-base percentage and 101st in slugging among qualified hitters.
• Jose Altuve has collected 36 base hits, an OBP of .299 and a slugging percentage of .364 this season.
• Jake Meyers has been key for Houston with 30 hits, an OBP of .351 plus a slugging percentage of .426.
• Meyers has safely hit in eight games in a row. In his last 10 games he is batting .364 with a double, a triple, two home runs, four walks and eight RBIs.

Reds Player Leaders

• Elly De La Cruz is batting .258 with five doubles, five home runs and 17 walks. He's slugging .391 with an on-base percentage of .339.
• Including all the qualifying hitters in the big leagues, his batting average ranks 66th, his on-base percentage ranks 68th, and he is 97th in slugging.
• TJ Friedl paces his team with a .388 slugging percentage. He has a batting average of .272 with an on-base percentage of .339.
• Including all qualifying players, he ranks 53rd in batting average, 68th in on-base percentage and 101st in slugging percentage.
• Gavin Lux has 36 hits with a .388 on-base percentage, leading the Reds in both categories.
• Jose Trevino is batting .310 with nine doubles, three home runs and five walks.

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