Astros vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 12

Odds updated as of 5:16 a.m.

The MLB schedule on Tuesday includes the Houston Astros taking on the Boston Red Sox.

All the information you need to make smart bets on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Red Sox Game Info

• Houston Astros (67-52) vs. Boston Red Sox (65-55)
• Date: Tuesday, August 12, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NESN

Astros vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-120) | BOS: (+102)
• Spread: HOU: -1.5 (+164) | BOS: +1.5 (-200)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Astros vs Red Sox Probable Starting Pitchers

Probable Pitchers: Spencer Arrighetti (Astros) - 1-2, 7.43 ERA vs Dustin May (Red Sox) - 6-8, 4.93 ERA

This contest's pitching matchup is set, as the Astros will send Spencer Arrighetti (1-2) to the mound, while Dustin May (6-8) will get the nod for the Red Sox. Arrighetti and his team have yet to cover the spread in any of their three chances this season. Arrighetti's team won his only start as a favorite this season. When May starts, the Red Sox are 6-13-0 against the spread. The Red Sox were the moneyline underdog for two May starts this season -- they lost both.

Astros vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (53.8%)

Astros vs Red Sox Moneyline

• Houston is a -120 favorite on the moneyline, while Boston is a +102 underdog on the road.

Astros vs Red Sox Spread

• The Red Sox are +1.5 on the run line against the Astros. The Red Sox are -200 to cover, and the Astros are +164.

Astros vs Red Sox Over/Under

• The over/under for Astros-Red Sox on Aug. 12 is 8.5. The over is -102, and the under is -120.

Bet on Houston Astros vs. Boston Red Sox on FanDuel today!

Astros vs Red Sox Betting Trends

• The Astros have been favorites in 77 games this season and have come away with the win 41 times (53.2%) in those contests.
• Oddsmakers have given Houston the best odds of winning it has seen this season, with a -120 moneyline listed for this contest.
• Contests with the Astros have gone over the total set by bookmakers in 52 of 118 chances this season.
• The Astros have an against the spread mark of 60-58-0 in 118 games with a line this season.
• The Red Sox have compiled a 20-23 record in games they were listed as the moneyline underdog (winning 46.5% of those games).
• Boston has never played a game this season with moneyline odds of +102 or longer.
• The Red Sox have combined with opponents to hit the over on the total 58 times this season for a 58-56-5 record against the over/under.
• The Red Sox have put together a 67-52-0 record ATS this season (covering 56.3% of the time).

Astros Player Leaders

• Jose Altuve leads Houston in slugging percentage (.474) thanks to 40 extra-base hits. He has a .287 batting average and an on-base percentage of .349.
• He ranks 19th in batting average, 45th in on-base percentage, and 37th in slugging among all qualifying hitters in the majors.
• Altuve hopes to build on a nine-game hitting streak in this matchup. In his last 10 games he is hitting .317 with a double, three home runs, five walks and six RBIs.
• Jeremy Pena has 111 hits and an OBP of .371, both of which lead the Astros this season. He's batting .314 and slugging .484.
• He ranks third in batting average, 16th in on-base percentage and 32nd in slugging in the major leagues.
• Yainer Diaz has 100 hits this season and has a slash line of .249/.277/.413.
• Christian Walker has been key for Houston with 102 hits, an OBP of .302 plus a slugging percentage of .399.
• Walker has hit safely in two games in a row. In his last five games he is batting .316 with three doubles, a home run, four walks and six RBIs.

Red Sox Player Leaders

• Jarren Duran has racked up an on-base percentage of .333 and a slugging percentage of .458. Both lead the Red Sox. He's batting .265.
• Including all the qualifying hitters in the majors, his batting average puts him 63rd, his on-base percentage is 68th, and he is 58th in slugging.
• Ceddanne Rafaela is hitting .259 with 24 doubles, three triples, 14 home runs and 20 walks. He's slugging .441 with an on-base percentage of .302.
• He is currently 76th in batting average, 130th in on-base percentage and 71st in slugging percentage among all qualifying batters.
• Trevor Story is batting .254 with 19 doubles, 18 home runs and 25 walks.
• Wilyer Abreu leads his team with 83 hits.

Astros vs Red Sox Head to Head

• 8/11/2025: 7-6 HOU (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/3/2025: 6-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/2/2025: 7-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 8/1/2025: 2-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/21/2024: 4-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2024: 6-5 BOS (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/19/2024: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)
• 8/11/2024: 10-2 HOU (Favorite: Astros, Spread: -1.5, Total: 10.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/10/2024: 5-4 HOU (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 8/9/2024: 8-4 HOU (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -136, Underdog Moneyline: +116)

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