Astros vs Red Sox Prediction, Odds, Moneyline, Spread & Over/Under for March 31

Odds updated as of 7:12 p.m.

The MLB's Tuesday slate includes the Houston Astros taking on the Boston Red Sox.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Astros vs Red Sox Game Info

• Houston Astros (3-2) vs. Boston Red Sox (1-3)
• Date: Tuesday, March 31, 2026
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NESN

Astros vs Red Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-154) | BOS: (+130)
• Spread: HOU: -1.5 (+142) | BOS: +1.5 (-172)
• Total: 7.5 -- Over: (-114) | Under: (-106)

Astros vs Red Sox Probable Starting Pitchers

Probable Pitchers: Hunter Brown (Astros) - 0-0, 0.00 ERA vs Brayan Bello (Red Sox) - 0-0, 0.00 ERA

The Astros will call on Hunter Brown against the Red Sox and Brayan Bello. Brown and his team failed to cover the spread in his only opportunity this season as a starter. Brown's team lost his only start as a favorite this season. Last season Bello and his team had a 17-12-0 record against the spread in games he pitched. Bello and his team went 4-9 in the 13 games he pitched when they were moneyline underdogs a season ago.

Astros vs Red Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (59.8%)

Astros vs Red Sox Moneyline

• Boston is the underdog, +130 on the moneyline, while Houston is a -154 favorite at home.

Astros vs Red Sox Spread

• The Astros are favored by 1.5 runs at home against the Red Sox. The Astros are +142 to cover the spread, while the Red Sox are -172.

Astros vs Red Sox Over/Under

• A total of 7.5 runs has been set for the Astros-Red Sox contest on March 31, with the over available at -114 and the under at -106.

Bet on Houston Astros vs. Boston Red Sox on FanDuel today!

Astros vs Red Sox Betting Trends

• The Astros were victorious in 53, or 53.5%, of the 99 contests they were chosen as favorites last season.
• Last season Houston came away with a win 18 times in 33 chances when named as a favorite of at least -154 or shorter on the moneyline.
• The Astros and their opponents hit the over in 72 of their 161 games with a total last season.
• The Red Sox won 26 of the 56 games they were the underdog on the moneyline last season (46.4%).
• When playing as a moneyline underdog with odds of +130 or longer last year, Boston went 9-12 (42.9%).
• The Red Sox combined with their opponents to go over the total 74 times last season for a 74-83-7 record against the over/under.

Astros Player Leaders

• Last season, Jose Altuve finished with a slugging percentage of .442, fueled by 51 extra-base hits.
• Jeremy Pena finished with an OBP of .363 and 150 total hits.
• Yainer Diaz ended his last campaign with 139 hits, an OBP of .284, plus a slugging percentage of .417.
• Christian Walker slashed .238/.297/.421 and finished with an OPS of .717.

Red Sox Player Leaders

• Jarren Duran had 41 doubles, 13 triples, 16 home runs and 60 walks while batting .256 last season.
• Trevor Story slugged .433 while batting .263.
• Ceddanne Rafaela had 34 doubles, four triples, 16 home runs and 28 walks while batting .249 last season.
• Caleb Durbin hit .256 with 25 doubles, 11 home runs and 30 walks.

Astros vs Red Sox Head to Head

• 3/30/2026: 8-1 HOU (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 8/13/2025: 4-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -156, Underdog Moneyline: +132)
• 8/12/2025: 14-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 8/11/2025: 7-6 HOU (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -162, Underdog Moneyline: +136)
• 8/3/2025: 6-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/2/2025: 7-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 8/1/2025: 2-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -126, Underdog Moneyline: +108)
• 8/21/2024: 4-1 BOS (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 8/20/2024: 6-5 BOS (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/19/2024: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -146, Underdog Moneyline: +124)

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