Astros vs Rangers Prediction, Odds, Moneyline, Spread & Over/Under for Sept. 15

Odds updated as of 7:12 p.m.

MLB action on Monday includes the Houston Astros playing the Texas Rangers.

We've got you covered, in terms of the vital info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Astros vs Rangers Game Info

• Houston Astros (81-69) vs. Texas Rangers (79-71)
• Date: Monday, September 15, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and RSN

Astros vs Rangers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-132) | TEX: (+112)
• Spread: HOU: -1.5 (+146) | TEX: +1.5 (-178)
• Total: 8.5 -- Over: (-102) | Under: (-120)

Astros vs Rangers Probable Starting Pitchers

Probable Pitchers: Jason Alexander (Astros) - 4-1, 4.18 ERA vs Jack Leiter (Rangers) - 9-8, 3.81 ERA

This contest's pitching matchup is set, as the Astros will send Jason Alexander (4-1) to the mound, while Jack Leiter (9-8) will get the nod for the Rangers. Alexander's team is 7-3-0 against the spread this season in his starts. Alexander's team is 4-1 this season when he starts and they are the moneyline favorite. When Leiter starts, the Rangers have gone 16-10-0 against the spread. The Rangers have a 5-13 record in Leiter's 18 starts this season when they were the underdog on the moneyline.

Astros vs Rangers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (58.6%)

Astros vs Rangers Moneyline

• Houston is a -132 favorite on the moneyline, while Texas is a +112 underdog on the road.

Astros vs Rangers Spread

• The Astros are hosting the Rangers and are favored by 1.5 runs (+146 to cover) on the runline. Texas is -178 to cover.

Astros vs Rangers Over/Under

• The over/under for Astros-Rangers on Sept. 15 is 8.5. The over is -102, and the under is -120.

Bet on Houston Astros vs. Texas Rangers on FanDuel today!

Astros vs Rangers Betting Trends

• The Astros have been favorites in 93 games this season and have come away with the win 49 times (52.7%) in those contests.
• This season Houston has been victorious 31 times in 56 chances when named as a favorite of at least -132 on the moneyline.
• The Astros and their opponents have gone over in 67 of their 149 games with a total set by sportsbooks this season.
• The Astros have posted a record of 74-75-0 against the spread this season.
• The Rangers have compiled a 30-45 record in games they were the underdog on the moneyline (winning 40% of those games).
• Texas has a record of 10-25 in games it has played as a moneyline underdog with odds of +112 or longer (28.6%).
• The Rangers have had an over/under set by oddsmakers 149 times, and have combined with opponents to go over the total in 66 of those games (66-81-2).
• The Rangers have put together an 82-67-0 record against the spread this season.

Astros Player Leaders

• Jose Altuve has an OPS of .770, fueled by an OBP of .327 and a team-best slugging percentage of .443 this season. He has a .264 batting average.
• Among qualifying hitters, he is 52nd in batting average, his on-base percentage ranks 79th, and he is 63rd in slugging.
• Altuve has picked up at least one hit in two straight games. During his last five outings he is hitting .267 with a home run and an RBI.
• Jeremy Pena leads Houston with 141 hits and an OBP of .356 this season. He's batting .297 and slugging .460.
• Among all qualified hitters, he ranks eighth in batting average, 26th in on-base percentage and 47th in slugging percentage.
• Pena enters this game looking to extend his three-game hit streak. During his last five outings he is batting .174 with two doubles, a walk and two RBIs.
• Yainer Diaz has collected 129 base hits, an OBP of .288 and a slugging percentage of .421 this season.
• Diaz enters this game with two games in a row with at least one hit. During his last five outings he is hitting .474 with two doubles, a home run and five RBIs.
• Christian Walker has 23 home runs, 81 RBI and a batting average of .239 this season.
• Walker brings a three-game hitting streak into this matchup. In his last five games he is hitting .368 with a home run, a walk and five RBIs.

Rangers Player Leaders

• Wyatt Langford has totaled 115 hits, a team-best for the Rangers. He's batting .242 and slugging .432 with an on-base percentage of .341.
• Including all the qualified hitters in the majors, he is 106th in batting average, 50th in on-base percentage and 74th in slugging percentage.
• Josh Smith's .343 on-base percentage and .372 slugging percentage are both team-highs. He has a batting average of .257.
• Including all qualified hitters, his batting average puts him 80th, his on-base percentage ranks 46th, and he is 130th in slugging.
• Adolis Garcia is batting .233 with 28 doubles, 18 home runs and 26 walks.
• Josh Jung has 19 doubles, a triple, 13 home runs and 25 walks while batting .248.

Astros vs Rangers Head to Head

• 9/7/2025: 4-2 TEX (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/6/2025: 11-0 HOU (Favorite: Rangers, Spread: -1.5, Total: 7, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 9/5/2025: 4-3 TEX (Favorite: Rangers, Spread: -1.5, Total: 8, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 7/13/2025: 5-1 TEX (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 7/12/2025: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 6.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 7/11/2025: 7-3 TEX (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 5/18/2025: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/17/2025: 5-1 TEX (Favorite: Rangers, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/16/2025: 6-3 HOU (Favorite: Rangers, Spread: -1.5, Total: 8, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 5/15/2025: 1-0 TEX (Favorite: Rangers, Spread: -1.5, Total: 7, Favorite Moneyline: -130, Underdog Moneyline: +110)

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