Astros vs Nationals Prediction, Odds, Moneyline, Spread & Over/Under for July 29

Odds updated as of 12:12 p.m.

Tuesday's slate in the MLB includes a matchup between the Houston Astros and the Washington Nationals.

Before you do any MLB betting on this matchup at FanDuel Sportsbook, here's everything you need to know.

Astros vs Nationals Game Info

• Houston Astros (60-47) vs. Washington Nationals (44-62)
• Date: Tuesday, July 29, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and MASN2

Astros vs Nationals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-136) | WSH: (+116)
• Spread: HOU: -1.5 (+146) | WSH: +1.5 (-178)
• Total: 8.5 -- Over: (-108) | Under: (-112)

Astros vs Nationals Probable Starting Pitchers

Probable Pitchers: Jason Alexander (Astros) - 1-1, 8.14 ERA vs Mike Soroka (Nationals) - 3-8, 4.85 ERA

The Astros will give the nod to Jason Alexander (1-1, 8.14 ERA), who is eyeing win No. 2 on the season, and the Nationals will turn to Mike Soroka (3-8, 4.85 ERA). Alexander has a record of 1-1-0 ATS in two starts with a spread this season. Alexander's team is 1-1 this season when he starts and they're favored on the moneyline. The Nationals are 5-10-0 against the spread when Soroka starts. The Nationals have a 3-11 record in Soroka's 14 starts this season when they were the underdog on the moneyline.

Astros vs Nationals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (57.4%)

Astros vs Nationals Moneyline

• Washington is a +116 underdog on the moneyline, while Houston is a -136 favorite at home.

Astros vs Nationals Spread

• The Astros are 1.5-run home favorites on the runline against the Nationals. The Astros are +146 to cover, and the Nationals are -178.

Astros vs Nationals Over/Under

• The over/under for Astros-Nationals on July 29 is 8.5. The over is -108, and the under is -112.

Bet on Houston Astros vs. Washington Nationals on FanDuel today!

Astros vs Nationals Betting Trends

• The Astros have been victorious in 39, or 53.4%, of the 73 contests they have been chosen as favorites in this season.
• This season Houston has come away with a win 22 times in 39 chances when named as a favorite of at least -136 on the moneyline.
• The Astros' games have gone over the total in 43 of their 106 opportunities.
• The Astros have an against the spread record of 53-53-0 in 106 games with a line this season.
• The Nationals have been the underdog on the moneyline 82 total times this season. They've gone 38-44 in those games.
• Washington has gone 28-35 in games it has played as a moneyline underdog with odds of +116 or longer (44.4%).
• The Nationals have played in 100 games with a set over/under, and have combined with their opponents to go over the total 55 times (55-43-2).
• The Nationals have covered 53% of their games this season, going 53-47-0 ATS.

Astros Player Leaders

• Jose Altuve has an OPS of .796, fueled by an OBP of .340 and a team-best slugging percentage of .455 this season. He has a .277 batting average.
• He ranks 37th in batting average, 59th in on-base percentage, and 55th in slugging among qualified hitters in MLB.
• Yainer Diaz has 14 doubles, a triple, 13 home runs and 15 walks. He's batting .244 and slugging .398 with an on-base percentage of .276.
• He ranks 112th in batting average, 153rd in on-base percentage and 107th in slugging among qualified hitters.
• Christian Walker has 90 hits this season and has a slash line of .233/.292/.381.
• Walker takes a three-game hitting streak into this matchup. In his last five games he is hitting .200 with two doubles, two walks and an RBI.
• Cam Smith is batting .258 with a .329 OBP and 43 RBI for Houston this season.

Nationals Player Leaders

• James Wood has accumulated a team-high OBP (.367) and slugging percentage (.501), while leading the Nationals in hits (103, while batting .263).
• Including all qualified players, he is 69th in batting average, while his on-base percentage is 21st and he is 20th in slugging.
• C.J. Abrams is hitting .272 with 23 doubles, four triples, 14 home runs and 26 walks. He's slugging .471 with an on-base percentage of .339.
• Including all qualified hitters, he ranks 47th in batting average, 61st in on-base percentage and 36th in slugging percentage.
• Luis Garcia is batting .262 with 22 doubles, eight home runs and 20 walks.
• Nathaniel Lowe is batting .226 with 16 doubles, two triples, 15 home runs and 39 walks.

Astros vs Nationals Head to Head

• 7/28/2025: 2-1 WSH (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 4/21/2024: 6-0 WSH (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -166, Underdog Moneyline: +140)
• 4/20/2024: 5-4 WSH (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -178, Underdog Moneyline: +150)
• 4/19/2024: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/14/2023: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 6/13/2023: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/15/2022: 8-0 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -196, Underdog Moneyline: +164)
• 5/14/2022: 13-6 WSH (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/13/2022: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)

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