Astros vs Marlins Prediction, Odds, Moneyline, Spread & Over/Under for Aug. 6

Odds updated as of 4:16 p.m.
The Wednesday slate in MLB includes a matchup between the Miami Marlins and the Houston Astros.
Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.
Marlins vs Astros Game Info
- Miami Marlins (55-57) vs. Houston Astros (64-50)
- Date: Wednesday, August 6, 2025
- Time: 4:40 p.m. ET
- Venue: loanDepot park -- Miami, Florida
- Coverage: FDSFL and SCHN
Marlins vs Astros Odds & Moneyline
- All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
- Moneyline: MIA: (-116) | HOU: (-102)
- Spread: MIA: +1.5 (-196) | HOU: -1.5 (+162)
- Total: 8.5 -- Over: (+102) | Under: (-124)
Marlins vs Astros Probable Starting Pitchers
Probable Pitchers: Janson Junk (Marlins) - 5-2, 3.86 ERA vs Spencer Arrighetti (Astros) - 1-1, 5.59 ERA
The Marlins will give the nod to Janson Junk (5-2, 3.86 ERA), who is eyeing win No. 6 on the season, and the Astros will turn to Spencer Arrighetti (1-1, 5.59 ERA). Junk and his team are 6-1-0 ATS this season when he starts. Junk has yet to start a game this season when his team was the moneyline favorite. Arrighetti has started two games with set spreads, and the Astros failed to cover in both opportunities. The Astros were the underdog on the moneyline for one Arrighetti start this season -- they lost.
Marlins vs Astros Prediction & Pick
All MLB win probability predictions and picks are according to numberFire.
Prediction: Marlins win (54.3%)
Marlins vs Astros Moneyline
- The moneyline numbers for Marlins vs. Astros reveal Miami as the favorite (-116) and Houston as the underdog (-102) on the road.
Marlins vs Astros Spread
- The Astros are 1.5-run favorites against the spread for this matchup with the Marlins. The Astros are +162 to cover, while the Marlins are -196 to cover as a 1.5-run underdog on the runline.
Marlins vs Astros Over/Under
- A total of 8.5 runs has been set for the Marlins-Astros contest on Aug. 6, with the over available at +102 and the under at -124.
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Marlins vs Astros Betting Trends
- The Marlins have been victorious in five, or 38.5%, of the 13 contests they have been chosen as favorites in this season.
- This season Miami has come away with a win five times in 12 chances when named as a favorite of at least -116 on the moneyline.
- The Marlins' games have gone over the total in 50 of their 108 opportunities.
- In 108 games with a line this season, the Marlins have a mark of 65-43-0 against the spread.
- The Astros have gone 21-13 in games they were listed as the moneyline underdog (winning 61.8% of those games).
- Houston has gone 16-11 when playing as a moneyline underdog with odds of -102 or longer (59.3%).
- The Astros have played in 113 games with a set over/under, and have combined with opponents to go over the total 48 times (48-61-4).
- The Astros have a 57-56-0 record against the spread this season (covering 50.4% of the time).
Marlins Player Leaders
- Kyle Stowers leads Miami in OBP (.370) and total hits (106) this season. He's batting .293 batting average while slugging .566.
- He is 14th in batting average, 18th in on-base percentage, and fifth in slugging among qualified hitters in MLB.
- Otto Lopez is hitting .244 with 14 doubles, 11 home runs and 35 walks. He's slugging .375 with an on-base percentage of .316.
- Among all qualifying hitters, he ranks 113th in batting average, 105th in on-base percentage and 132nd in slugging percentage.
- Xavier Edwards has hit one homer with a team-high .356 SLG this season.
- Agustin Ramirez is batting .239 with a .285 OBP and 50 RBI for Miami this season.
Astros Player Leaders
- Jose Altuve has a team-high .461 slugging percentage. He's batting .281 with an on-base percentage of .343.
- Including all the qualified hitters in the majors, his batting average is 26th, his on-base percentage ranks 53rd, and he is 53rd in slugging.
- Altuve brings a four-game hitting streak into this matchup. During his last five outings he is batting .238 with a home run, two walks and two RBIs.
- Jeremy Pena's 108 hits and .378 OBP both lead his team. He has a batting average of .322 while slugging .493.
- He is currently second in batting average, 12th in on-base percentage and 25th in slugging percentage among all qualifying hitters.
- Yainer Diaz is batting .255 with 16 doubles, a triple, 16 home runs and 15 walks.
- Jesus Sanchez is hitting .258 with 15 doubles, four triples, 10 home runs and 30 walks.
Marlins vs Astros Head to Head
- 8/5/2025: 7-3 HOU (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -108, Underdog Moneyline: -108)
- 8/4/2025: 8-2 HOU (Favorite: Marlins, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
- 7/11/2024: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -180, Underdog Moneyline: +152)
- 7/10/2024: 9-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -240, Underdog Moneyline: +198)
- 7/9/2024: 4-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -245, Underdog Moneyline: +200)
- 8/16/2023: 12-5 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
- 8/15/2023: 6-5 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -124, Underdog Moneyline: +106)
- 8/14/2023: 5-1 MIA (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
- 6/12/2022: 9-4 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -250, Underdog Moneyline: +205)
- 6/11/2022: 5-1 MIA (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -310, Underdog Moneyline: +250)
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