Astros vs Guardians Prediction, Odds, Moneyline, Spread & Over/Under for July 7

Odds updated as of 6:11 a.m.

The Monday schedule in MLB includes a matchup between the Houston Astros and the Cleveland Guardians.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Guardians Game Info

• Houston Astros (55-35) vs. Cleveland Guardians (40-48)
• Date: Monday, July 7, 2025
• Time: 8:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and CLEG

Astros vs Guardians Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-162) | CLE: (+136)
• Spread: HOU: -1.5 (+130) | CLE: +1.5 (-156)
• Total: 7.5 -- Over: (+102) | Under: (-124)

Astros vs Guardians Probable Starting Pitchers

Probable Pitchers: Colton Gordon (Astros) - 3-1, 4.37 ERA vs Tanner Bibee (Guardians) - 4-9, 4.10 ERA

The Astros will call on Colton Gordon (3-1) against the Guardians and Tanner Bibee (4-9). Gordon's team is 5-4-0 against the spread in his starts this season. Gordon's team has been victorious in 60% of the games he's started as the moneyline favorite with a record of 3-2. The Guardians have gone 8-8-0 against the spread when Bibee starts. The Guardians have been the underdog on the moneyline in eight of Bibee's starts this season, and they went 2-6 in those games.

Astros vs Guardians Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (68.4%)

Astros vs Guardians Moneyline

• Looking at the moneyline for Astros-Guardians, Houston is the favorite at -162, and Cleveland is +136 playing on the road.

Astros vs Guardians Spread

• The Guardians are at +1.5 on the runline against the Astros. The Guardians are -156 to cover the spread, and the Astros are +130.

Astros vs Guardians Over/Under

• The Astros-Guardians contest on July 7 has been given an over/under of 7.5 runs. The over is set at +102 and the under at -124.

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Astros vs Guardians Betting Trends

• The Astros have been chosen as favorites in 61 games this year and have walked away with the win 37 times (60.7%) in those games.
• Houston has a record of 11-7 in contests when bookmakers favor them by -162 or more on the moneyline.
• The Astros and their opponents have gone over the total this season in 36 of their 89 opportunities.
• The Astros are 47-42-0 against the spread in their 89 games that had a posted line this season.
• The Guardians have been the underdog on the moneyline 56 total times this season. They've gone 21-35 in those games.
• Cleveland has gone 4-12 in games it has played as a moneyline underdog with odds of +136 or longer (25%).
• The Guardians have played in 86 games with a set over/under, and have combined with their opponents to go over the total 36 times (36-47-3).
• The Guardians have put together a 42-44-0 record against the spread this season.

Astros Player Leaders

• Isaac Paredes has 12 doubles, a triple, 18 home runs and 44 walks while hitting .257. He has an on-base percentage of .356 and a slugging percentage of .467.
• Among qualified hitters in the majors, his batting average ranks 81st, his on-base percentage ranks 35th, and he is 45th in slugging.
• Paredes has recorded at least one hit in five straight games. During his last five outings he is batting .333 with two doubles, a home run, a walk and two RBIs.
• Jose Altuve is hitting .272 with 12 doubles, a triple, 16 home runs and 31 walks. He's slugging .457 with an on-base percentage of .332.
• Among all qualifying players, he ranks 50th in batting average, 71st in on-base percentage and 52nd in slugging percentage.
• Altuve enters this matchup looking to extend his five-game hit streak. During his last five outings he is hitting .500 with two doubles, a triple, three home runs, three walks and 10 RBIs.
• Jake Meyers has 89 hits this season and has a slash line of .308/.369/.405.
• Yainer Diaz has been key for Houston with 75 hits, an OBP of .280 plus a slugging percentage of .411.
• Diaz enters this game on a five-game hitting streak. In his last five games he is hitting .412 with two doubles, two home runs, two walks and three RBIs.

Guardians Player Leaders

• Jose Ramirez has racked up a team-best OBP (.360), while leading the Guardians in hits (95). He's batting .297 and slugging.
• Including all the qualifying hitters in MLB, his batting average ranks 13th, his on-base percentage ranks 29th, and he is 32nd in slugging.
• Steven Kwan's .419 slugging percentage paces his team. He has a batting average of .298 with an on-base percentage of .358.
• Including all qualified hitters, he ranks 11th in batting average, 31st in on-base percentage and 86th in slugging percentage.
• Carlos Santana is hitting .235 with seven doubles, 10 home runs and 39 walks.
• Kyle Manzardo has 11 doubles, two triples, 13 home runs and 25 walks while batting .217.

Astros vs Guardians Head to Head

• 6/8/2025: 4-2 CLE (Favorite: Guardians, Spread: -1.5, Total: 7.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/7/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 7, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 6/6/2025: 4-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/28/2024: 4-3 HOU (Favorite: Guardians, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/27/2024: 5-2 HOU (Favorite: Guardians, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/2/2024: 8-2 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 5/1/2024: 3-2 CLE (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 4/30/2024: 10-9 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 8/2/2023: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 8/1/2023: 2-0 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -200, Underdog Moneyline: +168)

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