Astros vs Athletics Prediction, Odds, Moneyline, Spread & Over/Under for July 26

Odds updated as of 10:13 a.m.

The MLB schedule on Saturday includes the Houston Astros facing the Athletics.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Athletics Game Info

• Houston Astros (60-44) vs. Athletics (44-62)
• Date: Saturday, July 26, 2025
• Time: 7:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and NBCS-CA

Astros vs Athletics Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-134) | OAK: (+114)
• Spread: HOU: -1.5 (+150) | OAK: +1.5 (-182)
• Total: 8.5 -- Over: (-128) | Under: (+104)

Astros vs Athletics Probable Starting Pitchers

Probable Pitchers: Hunter Brown (Astros) - 9-4, 2.57 ERA vs Jacob Lopez (Athletics) - 3-6, 4.60 ERA

The Astros will give the nod to Hunter Brown (9-4, 2.57 ERA), who is eyeing win No. 10 on the season, and the Athletics will turn to Jacob Lopez (3-6, 4.60 ERA). Brown and his team have a record of 12-8-0 against the spread when he starts. Brown's team has won 68.8% of his starts when they are favored on the moneyline (11-5). The Athletics have a 7-4-0 ATS record in Lopez's 11 starts that had a set spread. The Athletics are 6-4 in Lopez's 10 starts this season that they were the underdog on the moneyline.

Astros vs Athletics Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (66.7%)

Astros vs Athletics Moneyline

• The Astros vs Athletics moneyline has the Astros as a -134 favorite, while the Athletics are a +114 underdog on the road.

Astros vs Athletics Spread

• The Astros are 1.5-run favorites on the runline against the Athletics. The Astros are +150 to cover, while the Athletics are -182 to cover.

Astros vs Athletics Over/Under

• A combined run total of 8.5 has been set for Astros-Athletics on July 26, with the over at -128 and the under at +104.

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Astros vs Athletics Betting Trends

• The Astros have been chosen as favorites in 70 games this year and have walked away with the win 39 times (55.7%) in those games.
• This year, the Astros have won 23 of 38 games when listed as at least -134 or better on the moneyline.
• The Astros and their opponents have hit the over in 43 of their 103 games with a total this season.
• The Astros have an against the spread mark of 53-50-0 in 103 games with a line this season.
• The Athletics have won 32 of the 83 games they were listed as the moneyline underdog this season (38.6%).
• When playing as a moneyline underdog with odds of +114 or longer, the Athletics have a record of 18-39 (31.6%).
• The Athletics have combined with their opponents to hit the over on the total 55 times this season for a 55-45-5 record against the over/under.
• The Athletics are 53-52-0 against the spread this season.

Astros Player Leaders

• Jose Altuve leads Houston in slugging percentage (.463) thanks to 35 extra-base hits. He has a .280 batting average and an on-base percentage of .343.
• Among qualifying hitters in MLB, he is 32nd in batting average, 58th in on-base percentage, and 49th in slugging.
• Yainer Diaz has 14 doubles, a triple, 13 home runs and 14 walks. He's batting .246 and slugging .403 with an on-base percentage of .276.
• He ranks 111th in batting average, 155th in on-base percentage and 104th in slugging among qualifying batters.
• Christian Walker has collected 87 base hits, an OBP of .289 and a slugging percentage of .378 this season.
• Cam Smith has seven home runs, 43 RBI and a batting average of .263 this season.

Athletics Player Leaders

• Brent Rooker has accumulated 112 hits, a team-best for the Athletics. He's batting .273 and slugging .498 with an on-base percentage of .351.
• He ranks 49th in batting average, 45th in on-base percentage and 22nd in slugging percentage among all qualifying hitters in the majors.
• Jacob Wilson paces his team with a .354 OBP, and has a club-best .439 slugging percentage. He has a batting average of .312.
• He is currently fifth in batting average, 36th in on-base percentage and 71st in slugging percentage among all qualified batters.
• Tyler Soderstrom is batting .258 with 17 doubles, a triple, 19 home runs and 38 walks.
• Nick Kurtz has 18 doubles, two triples, 23 home runs and 28 walks while batting .305.

Astros vs Athletics Head to Head

• 7/25/2025: 15-3 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/24/2025: 5-2 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -148, Underdog Moneyline: +126)
• 6/19/2025: 6-4 OAK (Favorite: Astros, Spread: -1.5, Total: 10.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 6/18/2025: 11-4 HOU (Favorite: Astros, Spread: -1.5, Total: 9.5, Favorite Moneyline: -172, Underdog Moneyline: +144)
• 6/17/2025: 13-3 HOU (Favorite: Astros, Spread: -1.5, Total: 11, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 6/16/2025: 3-1 OAK (Favorite: Astros, Spread: -1.5, Total: 10, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/28/2025: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 5/27/2025: 11-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -240, Underdog Moneyline: +198)
• 9/12/2024: 6-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 9/11/2024: 5-4 OAK (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -235, Underdog Moneyline: +194)

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