Astros vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for July 29

Odds updated as of 9:13 a.m.

The MLB's Wednesday schedule includes the Houston Astros facing the Los Angeles Angels.

Here's what you need to know before checking out today's MLB odds and spreads on FanDuel Sportsbook.

Astros vs Angels Game Info

• Houston Astros (54-55) vs. Los Angeles Angels (42-66)
• Date: Wednesday, July 29, 2026
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: ABTV and SCHN

Astros vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-138) | LAA: (+118)
• Spread: HOU: -1.5 (+115) | LAA: +1.5 (-138)
• Total: 9.5 -- Over: (-115) | Under: (-105)

Astros vs Angels Probable Starting Pitchers

Probable Pitchers: Hayden Wesneski (Astros) - 0-0, 0.00 ERA vs Grayson Rodriguez (Angels) - 3-3, 8.54 ERA

The probable starters are Hayden Wesneski for the Astros and Grayson Rodriguez (3-3) for the Angels. Wesneski and his team were 4-2-0 against the spread when he pitched last season. Wesneski and his team won as favorites in 50% of his two appearances last season with a moneyline. The Angels have gone 5-4-0 against the spread when Rodriguez starts. The Angels have a 3-5 record in Rodriguez's eight starts this season when they were the underdog on the moneyline.

Astros vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (54.5%)

Astros vs Angels Moneyline

• The Astros vs Angels moneyline has Houston as a -138 favorite, while Los Angeles is a +118 underdog at home.

Astros vs Angels Spread

• The Angels are +1.5 on the run line against the Astros. The Angels are -138 to cover, and the Astros are +115.

Astros vs Angels Over/Under

• Astros versus Angels, on July 29, has an over/under of 9.5, with the over being -115 and the under -105.

Bet on Houston Astros vs. Los Angeles Angels on FanDuel today!

Astros vs Angels Betting Trends

• The Astros have been victorious in 19, or 48.7%, of the 39 contests they have been chosen as favorites in this season.
• This year Houston has won six of 18 games when listed as at least -138 on the moneyline.
• The Astros' games have gone over the total in 57 of their 109 opportunities.
• The Astros have an against the spread mark of 53-56-0 in 109 games with a line this season.
• The Angels have won 29 of the 81 games they were the moneyline underdog this season (35.8%).
• Los Angeles has a 17-32 record (winning only 34.7% of its games) when playing as a moneyline underdog of +118 or longer.
• In the 107 games oddsmakers have set an over/under for the Angels, they have combined with opponents to go over the total 48 times (48-57-2).
• The Angels have a 56-51-0 record against the spread this season (covering 52.3% of the time).

Astros Player Leaders

• Yordan Alvarez leads Houston with 126 hits and an OBP of .435, plus a team-best slugging percentage of .647. He's batting .325.
• Among all qualifying hitters in MLB, his batting average ranks second, his on-base percentage ranks first, and he is first in slugging.
• Alvarez hopes to build on a two-game hitting streak in this matchup. In his last five games he is hitting .250 with a home run, six walks and three RBIs.
• Isaac Paredes is hitting .255 with 18 doubles, a triple, 14 home runs and 41 walks. He's slugging .421 with an on-base percentage of .349.
• Among qualifying hitters, he ranks 75th in batting average, 49th in on-base percentage and 83rd in slugging percentage.
• Christian Walker has 91 hits this season and has a slash line of .235/.311/.455.
• Walker brings a two-game hitting streak into this matchup. During his last five outings he is hitting .263 with a double, a home run, two walks and four RBIs.
• Jeremy Pena is batting .314 with a .367 OBP and 30 RBI for Houston this season.
• Pena enters this game on a 10-game hitting streak. During his last 10 outings he is batting .439 with a double, five home runs, two walks and eight RBIs.

Angels Player Leaders

• Mike Trout has an on-base percentage of .394 and has 78 hits, both team-high numbers for the Angels. He's batting .244 and slugging .459.
• Including all qualifying hitters, he is 100th in batting average, while his on-base percentage is fifth and he is 46th in slugging.
• Zach Neto has 21 doubles, three triples, 19 home runs and 48 walks while hitting .234. He's slugging .437 with an on-base percentage of .325.
• He is 119th in batting average, 86th in on-base percentage and 69th in slugging percentage in the majors.
• Jo Adell has put up a team-high .401 slugging percentage.
• Nolan Schanuel is hitting .279 with 18 doubles, six home runs and 33 walks.

Astros vs Angels Head to Head

• 7/28/2026: 3-2 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 7/27/2026: 6-4 HOU (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 6/10/2026: 3-2 LAA (Favorite: Angels, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/9/2026: 10-1 LAA (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 6/8/2026: 5-4 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 3/29/2026: 9-7 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 3/28/2026: 11-9 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 3/27/2026: 6-2 LAA (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -174, Underdog Moneyline: +146)
• 3/26/2026: 3-0 LAA (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -184, Underdog Moneyline: +154)
• 9/28/2025: 6-2 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -116, Underdog Moneyline: -102)

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