Astros vs Angels Prediction, Odds, Moneyline, Spread & Over/Under for April 12

Odds updated as of 6:12 p.m.

The Houston Astros versus the Los Angeles Angels is on the MLB schedule for Saturday.

All the info you need to make smart wagers on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Astros vs Angels Game Info

• Houston Astros (6-7) vs. Los Angeles Angels (8-5)
• Date: Saturday, April 12, 2025
• Time: 7:10 p.m. ET
• Venue: Daikin Park -- Houston, Texas
• Coverage: SCHN and FDSSC

Astros vs Angels Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (-142) | LAA: (+120)
• Spread: HOU: -1.5 (+146) | LAA: +1.5 (-178)
• Total: 8.5 -- Over: (-124) | Under: (+102)

Astros vs Angels Probable Starting Pitchers

Probable Pitchers: Ryan Gusto (Astros) - 1-0, 1.13 ERA vs Tyler Anderson (Angels) - 0-0, 4.50 ERA

The Astros will give the ball to Ryan Gusto (1-0, 1.13 ERA), who is eyeing win No. 2 on the season, and the Angels will counter with Tyler Anderson. Gusto did not appear in a game when his team was the moneyline favorite last season. Anderson has started two games with set spreads, and the Angels covered in both opportunities. The Angels were the underdog on the moneyline for two Anderson starts this season -- they won both.

Astros vs Angels Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Astros win (61.1%)

Astros vs Angels Moneyline

• Looking at the moneyline for Angels-Astros, Los Angeles is the underdog at +120, and Houston is -142 playing at home.

Astros vs Angels Spread

• The Astros are hosting the Angels and are favored by 1.5 runs (+146 to cover) on the runline. Los Angeles is -178 to cover.

Astros vs Angels Over/Under

• The over/under for Astros-Angels on April 12 is 8.5. The over is -124, and the under is +102.

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Astros vs Angels Betting Trends

• The Astros have come away with three wins in the seven contests they have been listed as the favorites in this season.
• This year Houston has won one of three games when listed as at least -142 on the moneyline.
• The Astros' games have gone over the total in five of their 13 opportunities.
• In 13 games with a line this season, the Astros have a mark of 6-7-0 against the spread.
• The Angels have won 60% of the games this season they were the moneyline underdog (6-4).
• Los Angeles has won all three games it has played as a moneyline underdog with odds of +120 or longer.
• The Angels have combined with opponents to hit the over on the total nine times this season for a 9-4-0 record against the over/under.
• The Angels have a 7-6-0 record against the spread this season (covering 53.8% of the time).

Astros Player Leaders

• Jose Altuve leads Houston with 19 hits and an OBP of .383, plus a team-best slugging percentage of .500. He's batting .339.
• Among all qualifying hitters in baseball, he is 14th in batting average, 39th in on-base percentage, and 40th in slugging.
• Altuve has picked up at least one hit in six games in a row. In his last 10 games he is hitting .311 with three home runs, three walks and six RBI.
• Jeremy Pena has a double, two home runs and five walks. He's batting .196 and slugging .348 with an on-base percentage of .296.
• Among qualified batters, his batting average places him 140th, his on-base percentage 113th, and his slugging percentage 122nd.
• Pena takes a three-game streak with at least one hit into this matchup. During his last five outings he is batting .211 with a double, three walks and an RBI.
• Isaac Paredes has 14 hits this season and a team-best OBP of .383.
• Paredes has logged a hit or more in three games in a row. In his last five games he is batting .417 with a home run, two walks and three RBI.
• Yordan Alvarez has been key for Houston with 10 hits, an OBP of .333 plus a slugging percentage of .311.
• Alvarez heads into this game on a three-game hitting streak. In his last five games he is batting .375 with a home run, five walks and five RBI.

Angels Player Leaders

• Kyren Paris is hitting .419 with a double, a triple, five home runs and five walks. He's slugging 1.000 with an on-base percentage of .514.
• Mike Trout is hitting .208 with a double, six home runs and eight walks. He's slugging .604 with an on-base percentage of .322.
• His batting average ranks 120th among all qualified players, his on-base percentage is 88th, and he is 14th in slugging.
• Logan O'Hoppe has racked up a team-high slugging percentage (.698) while leading the Angels in hits (14).
• Taylor Ward is hitting .222 with a double, three home runs and four walks.

Astros vs Angels Head to Head

• 4/11/2025: 14-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 9/22/2024: 9-8 LAA (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -275, Underdog Moneyline: +225)
• 9/21/2024: 10-4 HOU (Favorite: Astros, Spread: -1.5, Total: 7.5, Favorite Moneyline: -230, Underdog Moneyline: +190)
• 9/20/2024: 9-7 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -255, Underdog Moneyline: +210)
• 9/19/2024: 3-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8, Favorite Moneyline: -290, Underdog Moneyline: +235)
• 9/15/2024: 6-4 HOU (Favorite: Astros, Spread: -1.5, Total: 9, Favorite Moneyline: -200, Underdog Moneyline: +168)
• 9/14/2024: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 9/13/2024: 5-3 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 6/9/2024: 9-7 LAA (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 6/8/2024: 6-1 HOU (Favorite: Astros, Spread: -1.5, Total: 8.5, Favorite Moneyline: -176, Underdog Moneyline: +148)

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