Arizona vs Iowa State College Basketball Prediction, Odds, Picks, Best Bets for Big 12 Tournament

The No. 1 seed Arizona Wildcats (30-2, 16-2 Big 12) and the No. 5 seed Iowa State Cyclones (27-6, 12-6 Big 12) will try to move on in the Big 12 tournament on Friday as they square off at 7 p.m. ET.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Arizona vs. Iowa State Game Info and Odds

• Game day: Friday, March 13, 2026
• Game time: 7 p.m. ET
• TV channel: ESPN
• Location: Kansas City, Missouri
• Arena: T-Mobile Center

Arizona vs. Iowa State Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Arizona win (59.6%)

If you plan to place a wager on Arizona-Iowa State outing (in which Arizona is a 3.5-point favorite and the over/under has been set at 143.5 points), keep reading for a few betting insights and trends for Friday's game.

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Arizona vs. Iowa State: ATS Betting Stats and Trends

• Arizona has compiled a 19-13-0 record against the spread this season.
• Iowa State is 19-14-0 ATS this year.
• Arizona covers the spread when it is a 3.5-point favorite or more 52% of the time. That's more often than Iowa State covers as an underdog of 3.5 or more (50%).
• The Wildcats have done a better job covering the spread in home games (9-8-0) than they have in road tilts (5-5-0).
• The Cyclones have performed better against the spread at home (9-8-0) than away (5-5-0) this season.
• Arizona has beaten the spread 11 times in 19 conference games.
• Iowa State's Big 12 record against the spread is 12-8-0.

Arizona vs. Iowa State: Moneyline Betting Stats

• Arizona has come away with 20 wins in the 22 contests it has been listed as the moneyline favorite in this season.
• This season, the Wildcats have been victorious 17 times in 18 chances when named as a favorite of at least -172 or shorter on the moneyline.
• Iowa State has been listed as the moneyline underdog just two other times so far this season, and it split the games.
• The Cyclones have played as a moneyline underdog of +142 or longer in only two games this season, which they split 1-1.
• Arizona has an implied victory probability of 63.2% according to the moneyline set by oddsmakers for this matchup.

Arizona vs. Iowa State Head-to-Head Comparison

• Arizona has a +583 scoring differential, topping opponents by 18.2 points per game. It is putting up 86.5 points per game to rank 14th in college basketball and is giving up 68.3 per outing to rank 44th in college basketball.
• Brayden Burries' team-leading 16.2 points per game ranks 208th in the nation.
• Iowa State outscores opponents by 17.2 points per game (posting 81.8 points per game, 56th in college basketball, and conceding 64.6 per outing, seventh in college basketball) and has a +568 scoring differential.
• Milan Momcilovic's team-leading 16.8 points per game rank him 167th in the nation.
• The 40.3 rebounds per game the Wildcats average rank second in college basketball, and are 12.4 more than the 27.9 their opponents pull down per contest.
• Tobe Awaka is 17th in college basketball play with 9.6 rebounds per game to lead the Wildcats.
• The Cyclones are 141st in the nation at 32.5 rebounds per game. That's 4.2 more than the 28.3 their opponents average.
• Joshua Jefferson leads the team with 7.7 rebounds per game (99th in college basketball).
• Arizona ranks 31st in college basketball by averaging 105.6 points per 100 possessions on offense, and defensively is fifth in college basketball, allowing 83.4 points per 100 possessions.
• The Cyclones score 106.6 points per 100 possessions (24th in college basketball), while allowing 84.2 points per 100 possessions (seventh in college basketball).

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