Angels vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 29

Odds updated as of 9:11 p.m.

The MLB slate on Wednesday includes the Los Angeles Angels facing the Chicago White Sox.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the most important information about this matchup.

Angels vs White Sox Game Info

• Los Angeles Angels (12-18) vs. Chicago White Sox (12-17)
• Date: Wednesday, April 29, 2026
• Time: 1:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and FDSW

Angels vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-120) | CHW: (+102)
• Spread: LAA: -1.5 (+138) | CHW: +1.5 (-166)
• Total: 8.5 -- Over: (-106) | Under: (-114)

Angels vs White Sox Probable Starting Pitchers

Probable Pitchers: Yusei Kikuchi (Angels) - 0-3, 6.21 ERA vs Erick Fedde (White Sox) - 0-3, 3.42 ERA

The probable starters are Yusei Kikuchi (0-3) for the Angels and Erick Fedde (0-3) for the White Sox. Kikuchi's team is 2-4-0 against the spread in his starts this season. This will be Kikuchi's first start this season with his team as the moneyline favorite. When Fedde starts, the White Sox are 1-2-0 against the spread. The White Sox were named the moneyline underdog for three Fedde starts this season -- they lost every game.

Angels vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Angels win (53.4%)

Angels vs White Sox Moneyline

• Looking at the moneyline for Angels-White Sox, Los Angeles is the favorite at -120, and Chicago is +102 playing at home.

Angels vs White Sox Spread

• The White Sox are at +1.5 on the runline against the Angels. The White Sox are -166 to cover the spread, and the Angels are +138.

Angels vs White Sox Over/Under

• A total of 8.5 runs has been set for the Angels-White Sox game on April 29, with the over available at -106 and the under at -114.

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Angels vs White Sox Betting Trends

• The Angels have been favorites in three games this season and have come away with the win two times (66.7%) in those contests.
• Los Angeles has been listed as a favorite of -120 or more on two occasions this season and won both games.
• Contests with the Angels have gone over the total set by sportsbooks in 16 of 29 chances this season.
• The Angels have an against the spread mark of 15-14-0 in 29 games with a line this season.
• The White Sox have been the moneyline underdog 24 total times this season. They've finished 9-15 in those games.
• Chicago has a 9-14 record (winning just 39.1% of its games) when playing as a moneyline underdog of +102 or longer.
• The White Sox have played in 27 games with an over/under set, and have combined with their opponents to go over the total 16 times (16-11-0).
• The White Sox are 13-14-0 against the spread this season.

Angels Player Leaders

• Mike Trout has 25 hits and an OBP of .422, both of which rank first among Los Angeles hitters this season. He has a .243 batting average and a slugging percentage of .553.
• Among qualifying batters in MLB, his batting average ranks 89th, his on-base percentage ranks eighth, and he is 14th in slugging.
• Trout hopes to build on a three-game hitting streak in this matchup. In his last five games he is batting .278 with a double, two home runs, seven walks and four RBIs.
• Zach Neto has eight doubles, five home runs and 20 walks. He's batting .242 and slugging .433 with an on-base percentage of .355.
• Among qualified batters, his batting average ranks him 92nd, his on-base percentage 52nd, and his slugging percentage 68th.
• Neto heads into this game looking to extend his two-game hit streak. During his last five outings he is batting .261 with three doubles, two walks and four RBIs.
• Jorge Soler is batting .232 with a .474 slugging percentage and 23 RBI this year.
• Soler takes a four-game hitting streak into this game. During his last five outings he is batting .263 with two doubles, a home run, two walks and four RBIs.
• Nolan Schanuel has been key for Los Angeles with 25 hits, an OBP of .298 plus a slugging percentage of .361.
• Schanuel heads into this game on a two-game hitting streak. During his last five outings he is batting .250 with two doubles, a home run and five RBIs.

White Sox Player Leaders

• Munetaka Murakami has a team-best OBP (.373), and leads the White Sox in hits (25). He's batting .243 and slugging.
• Including all the qualifying players in MLB, he ranks 89th in batting average, 31st in on-base percentage and seventh in slugging percentage.
• Miguel Vargas is batting .208 with four doubles, a triple, six home runs and 21 walks. He's slugging .446 with an on-base percentage of .352.
• He is 149th in batting average, 55th in on-base percentage and 64th in slugging percentage in MLB.
• Colson Montgomery is batting .225 with five doubles, seven home runs and 10 walks.
• Chase Meidroth is slugging .340 to pace his team.

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