Angels vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for March 27

Odds updated as of 4:12 p.m.

The Los Angeles Angels are among the MLB teams busy on Thursday, versus the Chicago White Sox.

All the information you need to make smart bets on this game at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Angels vs White Sox Game Info

• Los Angeles Angels (0-0) vs. Chicago White Sox (0-0)
• Date: Thursday, March 27, 2025
• Time: 4:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and FDSW

Angels vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-164) | CHW: (+138)
• Spread: LAA: -1.5 (-104) | CHW: +1.5 (-115)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Angels vs White Sox Probable Starting Pitchers

Probable Pitchers: Yusei Kikuchi (Angels) - 0-0, 0.00 ERA vs Sean Burke (White Sox) - 0-0, 0.00 ERA

The Angels will look to Yusei Kikuchi against the White Sox and Sean Burke. Kikuchi and his team were 14-18-0 ATS in his 32 appearances with a spread last season. Kikuchi and his team won 61.9% of the games he started as the moneyline favorite last season, with a record of 13-8. Last season Burke and his team had a 2-1-0 record against the spread when he pitched. Burke and his team had a 2-1 record in the three games he appeared in when they were moneyline underdogs a season ago.

Angels vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Angels win (53.3%)

Angels vs White Sox Moneyline

• The moneyline numbers for Angels vs. White Sox reveal Los Angeles as the favorite (-164) and Chicago as the underdog (+138) despite being the home team.

Angels vs White Sox Spread

• The White Sox are +1.5 on the spread (-115 to cover), and Los Angeles is -104 to cover the runline.

Angels vs White Sox Over/Under

• The Angels-White Sox contest on March 27 has been given an over/under of 7.5 runs. The over is set at -115 and the under at -105.

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Angels vs White Sox Betting Trends

• The Angels were favorites in 24 games last season and came away with the win nine times (37.5%) in those contests.
• Los Angeles was named as a favorite of -164 or more just one time last season and left with a loss in that game.
• The Angels and their opponents hit the over in 74 of their 159 games with a total last season.
• The White Sox won 21.8% of the games last season they were the moneyline underdog (32-115).
• Chicago went 24-92 in games it played as a moneyline underdog with odds of +138 or longer (20.7%).
• The White Sox combined with their opponents to go over the total 67 times last season for a 67-82-6 record against the over/under.

Angels Player Leaders

• Last season, Zachary Neto had 135 base hits, batting .249 with 58 extra-base hits.
• Taylor Ward had an OPS of .748, fueled by an OBP of .323 and a slugging percentage of .426.
• Jorge Soler ended his last campaign with 119 hits, an OBP of .338, plus a slugging percentage of .442.
• Nolan Schanuel had 130 hits and an OBP of .343.

White Sox Player Leaders

• Andrew Vaughn accumulated an OBP of .297 and a slugging percentage of .402 while collecting 140 hits last season.
• Andrew Benintendi hit .229 with 20 doubles, 20 home runs and 41 walks.
• Mike Tauchman hit .248 with 12 doubles, a triple, seven home runs and 47 walks a season ago.
• Josh Rojas hit .225 with 19 doubles, two triples, eight home runs and 46 walks.

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