3 Best MLB Strikeout Prop Bets for Wednesday 4/23/25

Within a given MLB slate, there are tons of strikeout props to sort through as there are lines posted for most of the day's starting pitchers.

Across today's action, which seem to present the best value in FanDuel Sportsbook's MLB betting odds?

We're going to dig into that today, laying out my favorite strikeout props across all the action. You can also do some research of your own by digging into our MLB player prop projections.

Please note lines and MLB projections are subject to change throughout the day after this article is published. All MLB odds come from FanDuel Sportsbook. All stats come from FanGraphs and Baseball Savant unless noted otherwise.

Today's Best MLB K Props

Eduardo Rodriguez Over 5.5 Strikeouts (-102)

For as shaky as Eduardo Rodriguez's tenure with the Arizona Diamondbacks began, he's pitching well right now, leading to value in his over tonight.

In four starts this year, Rodriguez has already gotten nine-plus strikeouts twice. Both starts were on the road, and one was against a Washington Nationals lineup that doesn't strike out much.

Since joining Arizona, Rodriguez has a respectable 23.8% strikeout rate. Tonight, that'll go up against a Tampa Bay Rays lineup that has a 23.9% strikeout rate against lefties since the start of last year, boosting expectations for Rodriguez.

Historically, pitchers projected near Rodriguez in my model have gone over 5.5 strikeouts at a rate of 54.7%, meaning the current market of -102 is a value.

Trevor Williams Over 4.5 Strikeouts (+126)

The sample on Trevor Williams pitching well continues to expand, and it leads to value in his over tonight against the Baltimore Orioles.

The gains for Williams began last year. In an injury-shortened season, he put up a 2.03 ERA across 13 starts with a 3.17 expected ERA. That latter number is 3.62 this year across four starts, meaning his 5.95 ERA is a bit unlucky.

The key to Williams' improvement is his sweeper. The league had just a .210 xwOBA against that pitch last year, according to Baseball Savant. That number would look unsustainable if it weren't even lower at .187 this year.

He has responded by throwing the sweeper 29.3% of the time to open this year, up from 21.1% last year. In 10 starts with lots of sweepers and sliders, Williams' strikeout rate is 21.7%.

It's a tough matchup as the Orioles don't strike out much. Still, I've got Williams projected at 4.83 strikeouts, putting him around a coin flip to go over 4.5 here.

JP Sears Over 4.5 Strikeouts (-108)

Although JP Sears' strikeout baseline isn't high, he is someone who can spike on occasion. He has done that often enough recently where I like his over against the Texas Rangers.

Part of the reason Sears doesn't get strikeouts is that he uses a sinker, which is almost always a low-whiff pitch. That's true for him, too, as it had just a 10.3% whiff rate last year.

Sears seems to recognize that as he has thrown the sinker just seven times all season. It's a shift he started to deploy last year. Across 18 starts with fewer sinkers, his strikeout rate has crept up to 19.5%.

That still isn't huge, but he's now at "home" against a team with a 24.2% strikeout rate against lefties since the start of last year. Add in a lofty pitch count, and my model has Sears projected at 5.35 strikeouts, enough for me to see value in the over.

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The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author's advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.