3 Best MLB Strikeout Prop Bets for Friday 4/25/25

Within a given MLB slate, there are tons of strikeout props to sort through as there are lines posted for most of the day's starting pitchers.

Across today's action, which seem to present the best value in FanDuel Sportsbook's MLB betting odds?

We're going to dig into that today, laying out my favorite strikeout props across all the action. You can also do some research of your own by digging into our MLB player prop projections.

Please note lines and MLB projections are subject to change throughout the day after this article is published. All MLB odds come from FanDuel Sportsbook. All stats come from FanGraphs and Baseball Savant unless noted otherwise.

Today's Best MLB K Props

Pablo Lopez Under 6.5 Strikeouts (-126)

With this being Pablo Lopez's first start off the IL, the expectation of a reduced pitch count is pushing me toward the under.

Lopez didn't miss a ton of time due to a hamstring strain, and he did make one rehab start. His pitch count there was just 63, though, so I'm not projecting Lopez for a full allotment of bullets tonight.

When I put Lopez down for 85 -- which I feel is fairly realistic -- his strikeout projection comes out at 5.41. The opposing Los Angeles Angels do whiff, but I'm not seeing enough here to get anywhere close to where the market has Lopez as of now.

Luis Severino Over 5.5 Strikeouts (+108)

It's not often we get to show value in betting on struggles for the Chicago White Sox's offense. Here, I think the market is actually a smidge too high on them for once.

Luis Severino will face that bunch in Sacramento. It gives him a matchup with an active roster that has a 25.9% strikeout rate against righties since the start of last year. Their mark of 24.1% in a small sample this year is also a good bit above average.

Although Severino is coming off a one-strikeout outing, he has been getting plenty of third strikes of late. When we expand the sample to look at his 19 starts with more cutters or sliders, his strikeout rate is 22.8%. Thus, I've got him going over this mark more than half the time, allowing us to take the plus money and fade this White Sox offense.

Matthew Liberatore Over 4.5 Strikeouts (-110)

Matthew Liberatore's return to the rotation has been a success so far, and I'm expecting more of the same tonight.

Across his first four starts, Liberatore has a 24.5% strikeout rate with an 11.5% swinging-strike rate. Both of those numbers are either up from or in line with last year when he was largely a reliever. He has mostly maintained the velocity on his four-seamer despite working in longer stints, and his slider has been a weapon with a 39.1% whiff rate, according to Baseball Savant.

Tonight, he'll face the Milwaukee Brewers, who are about as neutral as you can get from a matchup perspective. I've seen enough from Liberatore to think he can go over what is still a relatively modest mark.

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Which strikeout props stand out to you today? Check out FanDuel Sportsbook's MLB betting odds to see the full menu of options.

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The above author is a FanDuel employee and is not eligible to compete in public daily fantasy contests or place sports betting wagers on FanDuel. The advice provided by the author does not necessarily represent the views of FanDuel. Taking the author's advice will not guarantee a successful outcome. You should use your own judgment when participating in daily fantasy contests or placing sports wagers.