St. John's vs Seton Hall College Basketball Prediction, Odds, Picks, Best Bets for March 6

Big East action on Friday will see the the No. 18 St. John's Red Storm (24-6, 17-2 Big East) visit the Seton Hall Pirates (20-10, 10-9 Big East) at Prudential Center, tipping off at 9 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

St. John's vs. Seton Hall Game Info and Odds

• Game day: Friday, March 6, 2026
• Game time: 9 p.m. ET
• TV channel: Fox Sports 1
• Location: Newark, New Jersey
• Arena: Prudential Center

St. John's vs. Seton Hall Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: St. John's win (55.2%)

Here's a look at some betting trends and insights for St. John's (-4.5) versus Seton Hall on Friday. The total has been set at 136.5 points for this game.

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St. John's vs. Seton Hall: ATS Betting Stats and Trends

• St. John's has covered 16 times in 30 chances against the spread this season.
• Seton Hall is 18-12-0 ATS this year.
• When the spread is set as 4.5 or more this season, St. John's (12-12) covers a lower percentage of those games when it is the favorite (50%) than Seton Hall (5-1) does as the underdog (83.3%).
• In home games, the Red Storm have a worse record against the spread (8-9-0) compared to their ATS record in away games (6-3-0).
• The Pirates have been better against the spread on the road (9-2-0) than at home (6-10-0) this year.
• St. John's has 11 wins against the spread in 19 conference games this year.
• Seton Hall's Big East record against the spread is 11-8-0.

St. John's vs. Seton Hall: Moneyline Betting Stats

• St. John's has been chosen as the moneyline favorite in 25 games this year and has walked away with the win 22 times (88%) in those games.
• This season, the Red Storm have come away with a win 20 times in 23 chances when named as a favorite of at least -178 or better on the moneyline.
• Seton Hall has gone 3-6 in games it was the underdog on the moneyline (winning 33.3% of those games).
• The Pirates are 1-5 (winning only 16.7% of their games) when they have played as a moneyline underdog of +146 or longer.
• St. John's has an implied victory probability of 64% according to the moneyline set by sportsbooks for this matchup.

St. John's vs. Seton Hall Head-to-Head Comparison

• At 78.5 points scored per game and 65.8 points conceded last year, St. John's was 65th in college basketball on offense and 27th defensively.
• St. John's was the eighth-best team in the country in rebounds per game (36.9) and ranked 182nd in rebounds allowed (31.2) last season.
• St. John's was 53rd in the nation in assists (15.7 per game) last year.
• St. John's was 98th in the country in turnovers per game (10.3) and 17th-best in turnovers forced (14.2) last season.
• While Seton Hall ranked in the bottom 25 in the country in points per game last year with 61.6 (-4-worst), it ranked 119th in college basketball with 70.2 points given up per contest.
• Seton Hall averaged just 27.8 rebounds per game (14th-worst in college basketball), and allowed 31.3 rebounds per contest (187th-ranked).
• In terms of assists, Seton Hall put up just 11.2 per game (21st-worst in college basketball).
• Seton Hall averaged 11.5 turnovers per game (221st-ranked in college basketball). It forced 13.3 turnovers per contest (45th-ranked).

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