Rays vs White Sox Prediction, Odds, Moneyline, Spread & Over/Under for April 16

Odds updated as of 10:11 p.m.

The MLB's Thursday slate includes the Tampa Bay Rays taking on the Chicago White Sox.

We've got you covered, in terms of the most important info about this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Rays vs White Sox Game Info

• Tampa Bay Rays (9-7) vs. Chicago White Sox (6-11)
• Date: Thursday, April 16, 2026
• Time: 2:10 p.m. ET
• Venue: Rate Field -- Chicago, Illinois
• Coverage: CHSN and Rays.TV

Rays vs White Sox Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: TB: (-126) | CHW: (+108)
• Spread: TB: -1.5 (+128) | CHW: +1.5 (-154)
• Total: 8.5 -- Over: (-105) | Under: (-115)

Rays vs White Sox Probable Starting Pitchers

Probable Pitchers: Steven Matz (Rays) - 3-0, 3.94 ERA vs Anthony Kay (White Sox) - 1-0, 2.45 ERA

The Rays will give the nod to Steven Matz (3-0, 3.94 ERA), who is eyeing win No. 4 on the season, and the White Sox will counter with Anthony Kay (1-0, 2.45 ERA). Matz and his team have covered in each of the three games he's started with a spread this season. Matz's team is 2-0 this season when he starts and they're favored on the moneyline. Kay has started two games with set spreads, and the White Sox went 1-1-0. The White Sox were named the moneyline underdog for two Kay starts this season -- they split the games.

Rays vs White Sox Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Rays win (63.4%)

Rays vs White Sox Moneyline

• Tampa Bay is the favorite, -126 on the moneyline, while Chicago is a +108 underdog despite being at home.

Rays vs White Sox Spread

• The White Sox are +1.5 on the run line against the Rays. The White Sox are -154 to cover, and the Rays are +128.

Rays vs White Sox Over/Under

• The over/under for the Rays versus White Sox game on April 16 has been set at 8.5, with -105 odds on the over and -115 odds on the under.

Bet on Tampa Bay Rays vs. Chicago White Sox on FanDuel today!

Rays vs White Sox Betting Trends

• The Rays have been victorious in four of the eight contests they have been chosen as favorites in this season.
• Tampa Bay has been listed as a favorite of -126 or more on two occasions this season and split those games.
• The Rays and their opponents have hit the over in 12 of their 16 games with a total set by oddsmakers this season.
• The Rays have an against the spread mark of 9-7-0 in 16 games with a line this season.
• The White Sox have compiled a 5-11 record in games they were the underdog on the moneyline (winning 31.2% of those games).
• Chicago has gone 5-11 in games it has played as a moneyline underdog with odds of +108 or longer (31.2%).
• In the 16 games bookmakers have set an over/under for the White Sox, they have combined with opponents to go over the total nine times (9-7-0).
• The White Sox have a 6-10-0 record against the spread this season.

Rays Player Leaders

• Yandy Diaz has 23 hits and an OBP of .452, both of which are tops among Tampa Bay hitters this season. He has a .365 batting average and a slugging percentage of .556.
• Among qualified hitters in baseball, he ranks third in batting average, fourth in on-base percentage, and 20th in slugging.
• Diaz has picked up at least one hit in four games in a row. In his last five games he is batting .316 with a home run, two walks and five RBIs.
• Chandler Simpson has an OPS of .910, fueled by an OBP of .435 and a team-best slugging percentage of .475 this season. He's batting .407.
• Among qualifying hitters, he is first in batting average, eighth in on-base percentage and 52nd in slugging percentage.
• Simpson brings a nine-game streak with at least one hit into this matchup. In his last 10 outings he is batting .368 with a triple, a walk and three RBIs.
• Jonathan Aranda is batting .222 with a .413 slugging percentage and 14 RBI this year.
• Junior Caminero has two home runs, four RBI and a batting average of .233 this season.

White Sox Player Leaders

• Munetaka Murakami has accumulated nine hits with a .343 on-base percentage, leading the White Sox in both statistics. He's batting .167 and slugging .444.
• Including all qualifying hitters in the big leagues, he is 168th in batting average, 76th in on-base percentage and 69th in slugging percentage.
• Miguel Vargas is hitting .167 with three doubles, a triple, a home run and 10 walks. He's slugging .315 with an on-base percentage of .313.
• He is currently 168th in batting average, 117th in on-base percentage and 134th in slugging percentage among all qualifying hitters.
• Colson Montgomery is batting .186 with three doubles, three home runs and five walks.
• Chase Meidroth leads his team with a .305 slugging percentage.

Rays vs White Sox Head to Head

• 4/14/2026: 8-5 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 9/11/2025: 5-1 CHW (Favorite: Rays, Spread: -1.5, Total: 7.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 9/10/2025: 6-5 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -132, Underdog Moneyline: +112)
• 9/9/2025: 5-4 TB (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 7/23/2025: 11-9 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 7/21/2025: 8-3 CHW (Favorite: Rays, Spread: -1.5, Total: 9, Favorite Moneyline: -215, Underdog Moneyline: +180)
• 5/8/2024: 4-1 CHW (Favorite: Rays, Spread: -1.5, Total: 8.5, Favorite Moneyline: -260, Underdog Moneyline: +215)
• 5/7/2024: 5-1 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -270, Underdog Moneyline: +220)
• 5/6/2024: 8-2 TB (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -168, Underdog Moneyline: +142)
• 4/28/2024: 4-2 CHW (Favorite: Rays, Spread: -1.5, Total: 8, Favorite Moneyline: -148, Underdog Moneyline: +126)

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