Pirates vs Brewers Prediction, Odds, Moneyline, Spread & Over/Under for April 24

Odds updated as of 2:12 a.m.

The Friday slate in MLB includes a matchup between the Pittsburgh Pirates and the Milwaukee Brewers.

We've got you covered, in terms of the most important info regarding this game before you take a look at the MLB odds and spreads on FanDuel Sportsbook.

Pirates vs Brewers Game Info

• Pittsburgh Pirates (14-11) vs. Milwaukee Brewers (13-11)
• Date: Friday, April 24, 2026
• Time: 7:40 p.m. ET
• Venue: American Family Field -- Milwaukee, Wisconsin
• Coverage: Brewers.TV and SportsNet PT

Pirates vs Brewers Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: PIT: (-138) | MIL: (+118)
• Spread: PIT: -1.5 (+126) | MIL: +1.5 (-152)
• Total: 7 -- Over: (-110) | Under: (-110)

Pirates vs Brewers Probable Starting Pitchers

Probable Pitchers: Paul Skenes (Pirates) - 3-1, 3.27 ERA vs Brandon Woodruff (Brewers) - 2-0, 3.42 ERA

The Pirates will give the nod to Paul Skenes (3-1) against the Brewers and Brandon Woodruff (2-0). Skenes' team is 3-2-0 against the spread this season in his starts. Skenes' team has won 75% of his starts when they are favored on the moneyline (3-1). The Brewers have gone 3-1-0 ATS in Woodruff's four starts that had a set spread. The Brewers were the underdog on the moneyline for one Woodruff start this season -- they won.

Pirates vs Brewers Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Brewers win (52.4%)

Pirates vs Brewers Moneyline

• Looking at the moneyline for Brewers-Pirates, Milwaukee is the underdog at +118, and Pittsburgh is -138 playing on the road.

Pirates vs Brewers Spread

• The Pirates are at the Brewers and are favored by 1.5 runs on the spread. The Pirates are +126 to cover the runline, with the Brewers being -152.

Pirates vs Brewers Over/Under

• The over/under for the Pirates versus Brewers game on April 24 has been set at 7, with -110 odds on the over and -110 odds on the under.

Bet on Pittsburgh Pirates vs. Milwaukee Brewers on FanDuel today!

Pirates vs Brewers Betting Trends

• The Pirates have been favorites in 14 games this season and have come away with the win 10 times (71.4%) in those contests.
• Pittsburgh has a record of 4-3 when favored by -138 or more this year.
• Contests with the Pirates have gone over the total set by bookmakers in 14 of 25 chances this season.
• The Pirates are 15-10-0 against the spread in their 25 games that had a posted line this season.
• The Brewers have been the moneyline underdog 10 total times this season. They've finished 4-6 in those games.
• Milwaukee has played in three games as a moneyline underdog with odds of +118 or longer without a win.
• The Brewers have played in 24 games with an over/under set, and have combined with opponents to go over the total 14 times (14-10-0).
• The Brewers have a 15-9-0 record ATS this season (covering 62.5% of the time).

Pirates Player Leaders

• Oneil Cruz leads Pittsburgh in slugging percentage (.569) and total hits (29) this season. He's batting .284 with an on-base percentage of .348.
• Among all qualifying hitters in baseball, he ranks 38th in batting average, 64th in on-base percentage, and 12th in slugging.
• Cruz hopes to build on a three-game hitting streak in this matchup. During his last five outings he is batting .182 with a double, two home runs, a walk and four RBIs.
• Brandon Lowe has four doubles, seven home runs and 12 walks. He's batting .250 and slugging .548 with an on-base percentage of .351.
• Among qualified hitters, his batting average ranks him 83rd, his on-base percentage 61st, and his slugging percentage 20th.
• Ryan O'Hearn has 26 hits this season and a team-best OBP of .417.
• O'Hearn enters this matchup with four games in a row with at least one hit. In his last five games he is batting .294 with a home run, three walks and three RBIs.
• Bryan Reynolds has three home runs, 16 RBI and a batting average of .253 this season.

Brewers Player Leaders

• Brice Turang leads the Brewers with 23 hits. He's batting .280 and slugging .512 with an on-base percentage of .412.
• Including all qualified players in the majors, his batting average puts him 44th, his on-base percentage ranks 10th, and he is 29th in slugging.
• William Contreras paces his team with a .442 slugging percentage. He has a batting average of .291 with an on-base percentage of .371.
• His batting average is 31st among all qualified players, his on-base percentage is 30th, and he is 63rd in slugging.
• Jake Bauers is batting .237 with two doubles, five home runs and seven walks.
• Gary Sanchez is batting .236 with two doubles, a triple, five home runs and 13 walks.

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