Panthers vs Sabres NHL Prediction, Odds, Picks, Best Bets for Jan. 12

In NHL action on Monday, the Florida Panthers play the Buffalo Sabres.

Before you make your wager on FanDuel Sportsbook, we've got you covered with all the latest NHL betting insights.

Panthers vs Sabres Game Info

• Florida Panthers (23-18-3) vs. Buffalo Sabres (24-15-4)
• Date: Monday, January 12, 2026
• Time: 7 p.m. ET
• Venue: KeyBank Center -- Buffalo, New York
• Coverage: ESPN+

Panthers vs Sabres Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Panthers vs Sabres Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Sabres win (58.5%)

Panthers vs Sabres Puck Line

• The Sabres are underdogs by 1.5 goals. The Sabres are -260 to cover the spread, and the Panthers are +205.

Panthers vs Sabres Over/Under

• The over/under for the Panthers versus Sabres matchup on Jan. 12 has been set at 6.5, with +108 odds on the over and -132 odds on the under.

Panthers vs Sabres Moneyline

• The Panthers vs Sabres moneyline has Florida as a -113 favorite, while Buffalo is a -106 underdog at home.

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