Mets vs Twins Prediction, Odds, Moneyline, Spread & Over/Under for April 21

Odds updated as of 2:12 a.m.

On Tuesday in MLB, the New York Mets are playing the Minnesota Twins.

Before checking out the MLB betting lines on FanDuel Sportsbook, we've got you covered, in terms of the vital info about this matchup.

Mets vs Twins Game Info

• New York Mets (7-15) vs. Minnesota Twins (11-11)
• Date: Tuesday, April 21, 2026
• Time: 7:10 p.m. ET
• Venue: Citi Field -- Queens, New York
• Coverage: SNY and Twins.TV

Mets vs Twins Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: NYM: (-184) | MIN: (+154)
• Spread: NYM: -1.5 (+122) | MIN: +1.5 (-146)
• Total: 7.5 -- Over: (-115) | Under: (-105)

Mets vs Twins Probable Starting Pitchers

Probable Pitchers: Nolan McLean (Mets) - 1-1, 2.28 ERA vs Simeon Woods Richardson (Twins) - 0-3, 6.10 ERA

This contest's pitching matchup is set, as the Mets will send Nolan McLean (1-1) to the mound, while Simeon Woods Richardson (0-3) will take the ball for the Twins. When McLean starts, his team is 2-2-0 against the spread this season. McLean's team has a record of 1-2 this season when he starts and they are the favorite on the moneyline. The Twins have failed to cover all of the four games Woods Richardson has started that had a spread set by bookmakers. The Twins were named the moneyline underdog for three Woods Richardson starts this season -- they lost all of the games.

Mets vs Twins Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Mets win (60.4%)

Mets vs Twins Moneyline

• Looking at the moneyline for Twins-Mets, Minnesota is the underdog at +154, and New York is -184 playing at home.

Mets vs Twins Spread

• The Twins are at +1.5 on the runline against the Mets. The Twins are -146 to cover the spread, and the Mets are +122.

Mets vs Twins Over/Under

• A combined run total of 7.5 has been set for Mets-Twins on April 21, with the over at -115 and the under at -105.

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Mets vs Twins Betting Trends

• The Mets have won in five, or 35.7%, of the 14 contests they have been named as odds-on favorites in this year.
• New York has been listed as a favorite of -184 or more on two occasions this season and lost both games.
• The Mets' games have gone over the total in nine of their 22 opportunities.
• The Mets are 8-14-0 against the spread in their 22 games that had a posted line this season.
• The Twins have won 60% of the games this season they were the underdog on the moneyline (9-6).
• Minnesota has yet to play a game with moneyline odds of +154 or longer.
• In the 22 games bookmakers have set an over/under for the Twins, they have combined with opponents to go over the total 13 times (13-9-0).
• The Twins have gone 12-10-0 against the spread this season.

Mets Player Leaders

• Luis Robert is hitting .257 with two doubles, two home runs and 12 walks. He has an on-base percentage of .366 and a slugging percentage of .371.
• Among qualifying hitters in baseball, he ranks 75th in batting average, 47th in on-base percentage, and 111th in slugging.
• Robert will look for his fourth straight game with a hit in this contest. In his last five games he is hitting .200 with two doubles.
• Francisco Alvarez leads the Mets in OBP (.379) and total hits (15) this season. He's batting .268 while slugging .500.
• Among all qualified hitters, he is 60th in batting average, 31st in on-base percentage and 36th in slugging percentage.
• Francisco Lindor has 18 hits this season and has a slash line of .205/.293/.307.
• Marcus Semien has one home run, eight RBI and a batting average of .234 this season.
• Semien takes a four-game hitting streak into this game. In his last five games he is hitting .375 with a double, two walks and two RBIs.

Twins Player Leaders

• Josh Bell has accumulated a team-best slugging percentage (.447) and paces the Twins in hits (20). He's batting .263 and with an on-base percentage of .352.
• Including all qualified players in the big leagues, he is 67th in batting average, 67th in on-base percentage and 68th in slugging percentage.
• Bell enters this matchup on a three-game hitting streak. In his last five games he is batting .250 with an RBI.
• Ryan Jeffers has two doubles, a triple, two home runs and nine walks while batting .278. He's slugging .463 with an on-base percentage of .391.
• Luke Keaschall has three doubles, a home run and six walks while hitting .209.
• Austin Martin has three doubles, a home run and 14 walks while hitting .311.

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