Lightning vs Sabres NHL Prediction, Odds, Picks, Best Bets for April 6

The NHL slate on Monday includes the Tampa Bay Lightning taking on the Buffalo Sabres.

Get the latest NHL odds ahead of this matchup on FanDuel Sportsbook.

Lightning vs Sabres Game Info

• Tampa Bay Lightning (48-22-6) vs. Buffalo Sabres (46-23-8)
• Date: Monday, April 6, 2026
• Time: 7 p.m. ET
• Venue: KeyBank Center -- Buffalo, New York
• Coverage: NHL Network

Lightning vs Sabres Odds

All NHL odds, betting lines and prop bets are available on FanDuel Sportsbook.

Lightning vs Sabres Prediction & Pick

All NHL win probability predictions and picks are according to numberFire.

• Prediction: Lightning win (52.6%)

Lightning vs Sabres Puck Line

• The Sabres are underdogs by 1.5 goals (-250 to cover). And Tampa Bay, the favorite, is +198.

Lightning vs Sabres Over/Under

• The Lightning-Sabres matchup on April 6 has been given an over/under of 6.5 goals. The over is -106 and the under is -114.

Lightning vs Sabres Moneyline

• Looking at the moneyline for Sabres-Lightning, Buffalo is the underdog at -104, and Tampa Bay is -115 playing on the road.

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