Top 25 College Basketball Picks & Predictions Today - March 27

No. 1 Duke and No. 10 St. John's face off at 7:10 p.m. ET, which is one of four games on Friday that feature teams ranked in the Top 25 AP Poll. Check out all of the matchups below, along with our picks and projections.

If you're seeking additional betting info for today in March Madness, we have you covered with betting odds for each of the important games.

Duke vs. St. John's

• Matchup: No. 10 St. John's Red Storm vs. No. 1 Duke Blue Devils
• Projected Winner: Duke (65.03% win probability)
• Spread: Duke (-6.5)
• Time: 7:10 p.m. ET
• Date: March 27
• TV Channel: CBS

Bet on Duke vs. St. John's with FanDuel Sportsbook.

Michigan vs. Alabama

• Matchup: No. 18 Alabama Crimson Tide vs. No. 3 Michigan Wolverines
• Projected Winner: Michigan (72.12% win probability)
• Spread: Michigan (-8.5)
• Time: 7:35 p.m. ET
• Date: March 27
• TV Channel: TBS

Bet on Michigan vs. Alabama with FanDuel Sportsbook.

UConn vs. Michigan State

• Matchup: No. 11 Michigan State Spartans vs. No. 7 UConn Huskies
• Projected Winner: UConn (50.50% win probability)
• Spread: UConn (-1.5)
• Time: 9:45 p.m. ET
• Date: March 28
• TV Channel: CBS

Bet on UConn vs. Michigan State with FanDuel Sportsbook.

Iowa State vs. Tennessee

• Matchup: No. 23 Tennessee Volunteers vs. No. 6 Iowa State Cyclones
• Projected Winner: Iowa State (60.06% win probability)
• Spread: Iowa State (-4.5)
• Time: 10:10 p.m. ET
• Date: March 28
• TV Channel: TBS

Bet on Iowa State vs. Tennessee with FanDuel Sportsbook.

Matchup favorites and win projections are provided by numberFire.

For more college basketball betting insights, check out FanDuel Research's college basketball home page.

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