Clippers vs. Lakers Prediction, Odds, Picks, Best Bets for Jan. 22

Clippers vs. Lakers Game Info

• Date: Thursday, January 22, 2026
• Time: 10 p.m. ET
• Venue: Intuit Dome -- Inglewood, California
• Coverage: Amazon Prime Video

The Los Angeles Clippers (19-24) are slightly favored (by 2 points) to continue a three-game home winning streak when they host the Los Angeles Lakers (26-16) on Thursday, January 22, 2026 at 10 p.m. ET. The matchup has an over/under of 223.5.

Clippers vs. Lakers Odds & Spread

All NBA betting lines, odds and prop bets are from FanDuel Sportsbook.

Clippers vs. Lakers Prediction & Pick

All NBA win probability predictions and picks are according to numberFire.
Prediction: Clippers win (55.7%)

Clippers vs. Lakers Betting Trends

• The Clippers have covered the spread 20 times this season (20-23-0).
• The Lakers are 22-19-1 against the spread this season.
• Clippers games have finished with a final combined score above the over/under 23 times out of 42 chances this season.
• Lakers games this year have hit the over on 25 of 42 set point totals (59.5%).
• The Clippers own a worse record against the spread in home games (9-11-0) than they do in away games (11-12-0).
• The Clippers have hit the over on the total in 10 of 20 home games (50%). They've done better in road games, eclipsing the total in 13 of 23 matchups (56.5%).
• This season, the Lakers are 10-9-1 at home against the spread (.500 winning percentage). Away, they are 12-10-0 ATS (.545).
• Lakers games have gone above the over/under more frequently at home (15 times out of 20) than away (10 of 22) this season.

Clippers Leaders

• James Harden averages 26 points, 4.8 boards and 8 assists.
• Kawhi Leonard is averaging 28.2 points, 3.5 assists and 6.3 boards.
• Ivica Zubac is averaging 14.8 points, 10.8 rebounds and 2.4 assists. At the other end, he averages 0.4 steals and 0.9 blocked shots.
• John Collins is averaging 13.3 points, 4.9 rebounds and 0.8 assists.
• Kris Dunn is averaging 8 points, 3 boards and 3.2 assists. Defensively, he averages 1.5 steals (eighth in league) and 0.2 blocked shots.

Lakers Leaders

• Per game, Luka Doncic provides the Lakers 33.5 points, 7.7 boards and 8.7 assists. He also averages 1.6 steals (fifth in league) and 0.5 blocks.
• The Lakers are getting 13.9 points, 8.8 boards and 0.9 assists per game from Deandre Ayton.
• The Lakers are getting 22.5 points, 6 boards and 7 assists per game from LeBron James.
• Jake Laravia's numbers on the season are 9.5 points, 4.2 rebounds and 2 assists per contest. He is draining 46.3% of his shots from the floor and 33.6% from beyond the arc, with an average of 1.2 treys.
• Marcus Smart's numbers on the season are 10 points, 3.1 boards and 2.8 assists per contest. He is making 40.7% of his shots from the field and 32.7% from beyond the arc, with an average of 1.7 treys.

For more NBA betting insights, check out FanDuel Research's NBA home page.

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