Cardinals vs Giants Prediction, Odds, Moneyline, Spread & Over/Under for June 22

Odds updated as of 2:11 PM

The MLB slate on Saturday includes the St. Louis Cardinals facing the San Francisco Giants.

All the info you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Cardinals vs Giants Game Info

• St. Louis Cardinals (37-37) vs. San Francisco Giants (36-40)
• Date: Saturday, June 22, 2024
• Time: 2:15 PM ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: NBCS-BA

Cardinals vs Giants Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: STL: (-110) | SF: (-106)
• Spread: STL: +1.5 (-172) | SF: -1.5 (+142)
• Total: 8.5 -- Over: (-122) | Under: (-100)

Cardinals vs Giants Probable Starting Pitchers

Probable Pitchers: Miles Mikolas (Cardinals) - 5-6, 4.59 ERA vs Jordan Hicks (Giants) - 4-3, 2.82 ERA

This contest's pitching matchup is set, as the Cardinals will send Miles Mikolas (5-6) to the mound, while Jordan Hicks (4-3) will get the nod for the Giants. Mikolas' team is 8-7-0 against the spread in his starts this season. Mikolas and his team have lost each of the four games he's started as the moneyline favorite. The Giants are 8-7-0 against the spread when Hicks starts. The Giants have a 3-3 record in Hicks' six starts this season when they were the moneyline underdog.

Cardinals vs Giants Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Giants win (53.2%)

Cardinals vs Giants Moneyline

• San Francisco is a -106 underdog on the moneyline, while St. Louis is a -110 favorite at home.

Cardinals vs Giants Spread

• The Giants are 1.5-run favorites against the spread for this matchup with the Cardinals. The Giants are +142 to cover, while the Cardinals are -172 to cover as a 1.5-run underdog on the runline.

Cardinals vs Giants Over/Under

• An over/under of 8.5 has been set for Cardinals-Giants on June 22, with the over being -122 and the under -100.

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Cardinals vs Giants Betting Trends

• The Cardinals have come away with 15 wins in the 32 contests they have been listed as the favorites in this season.
• St. Louis has a record of 15-17 in contests when bookmakers favor them by -110 or more on the moneyline.
• The Cardinals and their opponents have gone over the total this season in 30 of their 71 opportunities.
• In 71 games with a line this season, the Cardinals have a mark of 35-36-0 against the spread.
• The Giants have won 45.5% of the games this season they were the underdog on the moneyline (15-18).
• San Francisco has a 14-17 record (winning 45.2% of its games) when playing as a moneyline underdog of -106 or longer.
• In the 75 games bookmakers have set an over/under for the Giants, they have combined with opponents to go over the total 39 times (39-34-2).
• The Giants have a 36-39-0 record against the spread this season (covering 48% of the time).

Cardinals Player Leaders

• Brendan Donovan leads St. Louis with a slugging percentage of .402, fueled by 24 extra-base hits. He has a .258 batting average and an on-base percentage of .327.
• Among qualifying hitters, he is 63rd in batting average, his on-base percentage ranks 65th, and he is 87th in slugging.
• Donovan has hit safely in five straight games. In his last five games he is hitting .409 with a double, two home runs and seven RBI.
• Nolan Arenado has hit six homers this season while driving in 32 runs. He's batting .260 this season and slugging .375 with an on-base percentage of .315.
• He is 58th in batting average, 90th in on-base percentage and 111th in slugging in the majors.
• Alec Burleson has 63 hits and is batting .273 this season.
• Masyn Winn has 68 hits this season and a team-best OBP of .339.
• Winn enters this matchup on a three-game hitting streak. During his last five outings he is hitting .217 with a double, a home run, a walk and two RBI.

Giants Player Leaders

• Thairo Estrada has accumulated a team-best .396 slugging percentage. He's batting .240 with an on-base percentage of .272.
• He is 100th in batting average, 146th in on-base percentage and 95th in slugging percentage among all qualifying hitters in MLB.
• Matt Chapman has 19 doubles, eight home runs and 29 walks while hitting .227. He's slugging .379 with an on-base percentage of .306.
• Including all qualified hitters, he ranks 121st in batting average, 104th in on-base percentage and 108th in slugging percentage.
• Jorge Soler has racked up an on-base percentage of .317 and has 51 hits, both team-high figures for the Giants.
• Heliot Ramos has seven doubles, 10 home runs and 18 walks while batting .307.

Cardinals vs Giants Head to Head

• 6/20/2024: 6-5 STL (Favorite: Giants, Spread: -1.5, Total: 9, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/27/2023: 6-0 STL (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -158, Underdog Moneyline: +134)
• 4/26/2023: 7-3 SF (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 4/25/2023: 5-4 SF (Favorite: Giants, Spread: -1.5, Total: 9.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 4/24/2023: 4-0 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -110, Underdog Moneyline: -106)
• 5/15/2022: 15-6 STL (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -138, Underdog Moneyline: +118)
• 5/14/2022: 4-0 STL (Favorite: Giants, Spread: -1.5, Total: 8.5, Favorite Moneyline: -116, Underdog Moneyline: -102)
• 5/13/2022: 8-2 SF (Favorite: Giants, Spread: -1.5, Total: 7.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/8/2022: 4-3 SF (Favorite: Giants, Spread: -1.5, Total: 8, Favorite Moneyline: -134, Underdog Moneyline: +114)
• 5/7/2022: 13-7 SF (Favorite: Giants, Spread: -1.5, Total: 7, Favorite Moneyline: -136, Underdog Moneyline: +116)

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