Angels vs Padres Prediction, Odds, Moneyline, Spread & Over/Under for April 17

Odds updated as of 6:13 a.m.

The MLB slate on Friday includes the Los Angeles Angels taking on the San Diego Padres.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's what you need to know.

Angels vs Padres Game Info

• Los Angeles Angels (10-10) vs. San Diego Padres (13-6)
• Date: Friday, April 17, 2026
• Time: 9:38 p.m. ET
• Venue: Angel Stadium -- Anaheim, California
• Coverage: FDSW and Padres.TV

Angels vs Padres Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: LAA: (-142) | SD: (+120)
• Spread: LAA: -1.5 (+146) | SD: +1.5 (-178)
• Total: 8.5 -- Over: (-115) | Under: (-105)

Angels vs Padres Probable Starting Pitchers

Probable Pitchers: José Soriano (Angels) - 4-0, 0.33 ERA vs Matt Waldron (Padres) - 0-0, 0.00 ERA

The Angels will give the nod to Jose Soriano (4-0) against the Padres and Matt Waldron. Soriano's team has covered the spread in each of the four opportunities this season. This will be Soriano's first start this season with his team as the moneyline favorite. Last season Waldron pitched in one game with a spread, which his team did not cover. Waldron's team was the moneyline underdog just one time in a game he pitched a season ago, and lost.

Angels vs Padres Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Padres win (52.7%)

Angels vs Padres Moneyline

• Looking at the moneyline for Angels-Padres, Los Angeles is the favorite at -142, and San Diego is +120 playing on the road.

Angels vs Padres Spread

• The Padres are +1.5 on the run line against the Angels. The Padres are -178 to cover, and the Angels are +146.

Angels vs Padres Over/Under

• The over/under for Angels-Padres on April 17 is 8.5. The over is -115, and the under is -105.

Bet on Los Angeles Angels vs. San Diego Padres on FanDuel today!

Angels vs Padres Betting Trends

• The Angels have yet to play a game this season where they are listed as the favorite to win.
• Los Angeles has not played a game this season with better moneyline odds than -142.
• The Angels' games have gone over the total in 12 of their 20 opportunities.
• The Angels have posted a record of 12-8-0 against the spread this season.
• The Padres have compiled a 5-4 record in games they were the underdog on the moneyline (winning 55.6% of those games).
• San Diego has gone 2-1 in games it has played as a moneyline underdog with odds of +120 or longer (66.7%).
• The Padres have played in 19 games with a set over/under, and have combined with their opponents to go over the total nine times (9-9-1).
• The Padres have covered 73.7% of their games this season, going 14-5-0 against the spread.

Angels Player Leaders

• Mike Trout has 17 hits and an OBP of .416, both of which lead Los Angeles hitters this season. He has a .246 batting average and a slugging percentage of .594.
• Among all qualifying hitters in baseball, his batting average ranks 90th, his on-base percentage ranks 14th, and he is 13th in slugging.
• Trout hopes to build on a six-game hitting streak in this matchup. During his last 10 games he is hitting .275 with three doubles, five home runs, seven walks and 13 RBIs.
• Zach Neto is hitting .238 with four doubles, five home runs and 14 walks, while slugging .475 with an on-base percentage of .358.
• Among qualified batters, his batting average places him 102nd, his on-base percentage 53rd, and his slugging percentage 49th.
• Neto has picked up a hit in two games in a row. During his last five outings he is batting .158 with a double, five walks and an RBI.
• Jo Adell leads Los Angeles in slugging percentage (.432) powered by four extra-base hits.
• Oswald Peraza is batting .269 with a .345 OBP and eight RBI for Los Angeles this season.

Padres Player Leaders

• Jackson Merrill is batting .260 with six doubles, three home runs and six walks. He's slugging .466 with an on-base percentage of .316.
• Including all qualified hitters, he ranks 73rd in batting average, while his on-base percentage ranks 114th and he is 55th in slugging.
• Merrill takes a six-game hitting streak into this game. In his last 10 games he is hitting .268 with five doubles, a home run, four walks and seven RBIs.
• Ramon Laureano paces his team with 20 hits and has a club-leading .551 slugging percentage. He has a batting average of .290 with an on-base percentage of .355.
• Including all qualifying hitters, he is 40th in batting average, 55th in on-base percentage and 23rd in slugging percentage.
• Xander Bogaerts has two doubles, three home runs and six walks while hitting .268.
• Manny Machado leads his team with a .368 OBP.

Sign up for FanDuel Sportsbook and FanDuel Daily Fantasy today!