Wyoming vs Illinois Prediction, Odds & Betting Trends for College Football Week 0 Game on FanDuel (Aug 27)

Wyoming vs Illinois Week 0 Game Info

2022 NCAA College Football Game
Wyoming Cowboys (0-0, 0-0) vs. Illinois Fighting Illini (0-0, 0-0)
Date: Saturday, August 27, 2022
Time: 4 p.m. ET
Venue: Memorial Stadium — Champaign, IL
Coverage: BTN

Week 0 of the 2022 NCAA college football season includes a showdown between the Wyoming Cowboys and Illinois Fighting Illini. Wyoming's 2021 was filled with highs and lows, culminating with a Famous Idaho Potato Bowl victory over Kent State.

Meanwhile, Illinois hopes to bounce back after finishing as the third-worst team in the Big Ten's West Division last year. Second-year coach Bret Bielema brought in Barry Lunney Jr. as his offensive coordinator this year, so it remains to be seen if the Fighting Illini can generate more than the 20.2 points that they averaged in 2021 (No. 111).

Wyoming vs Illinois Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: WYO: (+350) | ILL: (-450)
Spread: WYO: +9.5 (+100) | ILL: -9.5 (-120)
Total: 43.5 — Over: (-120) | Under: (+100)

Illinois enters this contest as the favorite on the moneyline and the spread. This 4 p.m. ET clash also features a total of 43.5, which is the lowest of this week's college football projected totals.

Wyoming vs Illinois Prediction & Pick

While Wyoming had the better end to their 2021 NCAAF campaign, Illinois is the better team here. The Cowboys have proven in the past that they have a tough time handling Big Ten schools, going 0-6 straight up in their last six games against the conference's teams.

Meanwhile, the Fighting Illini usually start their campaigns off right. Illinois is 10-1 straight up in its last 11 first games of the season. It may not be the highest-scoring game of the week, but I expect Illinois to put on a dominant performance at home.

Final Score Prediction: Illinois: 32 | Wyoming: 14

Wyoming vs Illinois Betting Trends

- Wyoming is 4-10 straight up in its last 14 road games.
- Illinois is 4-1 against the spread (ATS) in its last five games.
- The total has hit the over in five of Wyoming's last six games.
- The total has hit the under in seven of Illinois' last nine games played on Saturday.

Wyoming vs Illinois Best Bet

All NCAAF betting lines, odds and prop bets are available on FanDuel Sportsbook.

Again, Illinois rarely loses its first game of the season, which is a trend I expect to continue. I don't think Wyoming has the offense to keep up with his counterpart, which should lead to the Fighting Illini covering the 9.5-point spread in the end.

Bet: Illinois -9.5 (-120)

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.