Saints vs Cardinals Prediction, Odds & Betting Trends for NFL Week 7 Thursday Night Football on FanDuel Sportsbook

Saints vs Cardinals Week 7 Game Info

2022 NFL Regular Season — Week 7 Thursday Night Football
New Orleans Saints (2-4, 1-1 Away) vs. Arizona Cardinals (2-4, 0-3 Home)
Date: Thursday, October 20, 2022
Time: 8:15 p.m. ET
Venue: State Farm Stadium — Glendale, AZ
Coverage: Prime Video

Two teams looking to get back on track in the NFC playoff race meet head-to-head in Week 7 as the New Orleans Saints visit the Arizona Cardinals. The Saints fell to the Cincinnati Bengals by a score of 30-26 in Week 6 despite the fact that they averaged an impressive 6.7 yards per carry on the ground.

Meanwhile, the Cardinals struggled to get anything going on offense on Sunday and it led to a 19-9 defeat at the hands of the Seattle Seahawks. Arizona has now lost three of its last four games and quarterback Kyler Murray has only thrown 6 touchdowns compared to 4 interceptions this season.

Saints vs Cardinals Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: NO: (+100) | ARI: (-118)
Spread: NO: +1.5 (-110) | ARI: -1.5 (-110)
Total: 44.5 — Over: (-115) | Under: (-105)

The Cardinals enter this contest as a slight home favorite on the moneyline and the spread. This Thursday night clash also features one of the lower totals on the Week 7 slate at 44.5 points.

Saints vs Cardinals Prediction & Pick

Both of these teams enter Week 7 in desperate need of a win. Falling three games under .500 would make the mountain to climb back up that much higher. I'll give the edge to the Cardinals here for one reason and one reason only. Injuries continue to pile up with every week that passes for the Saints.

Quarterbacks Jameis Winston and Andy Dalton are each dealing with back issues. Wide receivers Michael Thomas, Chris Olave and Jarvis Landry will likely not suit up on Thursday night. Pressure will be put on running back Alvin Kamara and utility man Taysom Hill, but their efforts won't be enough.

Final Score Prediction: Saints: 20 | Cardinals: 28

Saints vs Cardinals Betting Trends

- New Orleans is 5-2 straight up in its last seven games against Arizona.
- The total has hit the over in five of New Orleans' last seven games.
- Arizona is 9-2 against the spread (ATS) in its last 11 games played in October.
- The total has hit the over in six of Arizona's last eight games against New Orleans.

Saints vs Cardinals Best Bet

All NFL betting lines, odds and prop bets are available on FanDuel Sportsbook.

The Cardinals have lost a ridiculous eight straight home games, which means backing them on the moneyline comes with way too much risk here. Shifting gears to the point total is a logical move to make. These are two defenses that rank outside the top 20 in points allowed per game this season.

The over has hit in six of the last eight matchups between the Saints and Cardinals. It has also hit in four of New Orleans' six games this year. Those six games have combined to see an average of 49.8 total points scored. Look for these offenses to reach the end zone just enough times on Thursday.

Bet: Over 44.5 Points (-115)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.