NFL Week 4 Picks & Predictions Against the Spread From The Duel Staff (2022)

The 2022 NFL season is rolling along for Week 4 and the editors at The Duel are making against the spread (ATS) picks for each and every game. You can follow along, check it out or fade us throughout the season.

NFL Week 4 Predictions

We have full betting previews for each matchup below along with the betting lines from FanDuel Sportsbook's NFL odds. We’ll update this with records on a weekly basis and make picks for every step of the way, including the playoffs and Super Bowl.

NFL Expert Picks Against the Spread

Note: All betting lines and odds are from FanDuel Sportsbook, as of Thursday, Sept. 29 at 10 a.m. ET.

Vikings vs Saints Picks

Vikings (-2.5) vs Saints (+2.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Vikings
- Isaiah De Los Santos: Vikings
- Tyler Maher: Vikings

Browns vs Falcons Picks

Browns (-1.5) vs Falcons (+1.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Browns
- Isaiah De Los Santos: Browns
- Tyler Maher: Browns

Commanders vs Cowboys Picks

Commanders (+3) vs Cowboys (-3) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Cowboys
- Isaiah De Los Santos: Cowboys
- Tyler Maher: Cowboys

Seahawks vs Lions Picks

Seahawks (+4.5) vs Lions (-4.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Lions
- Isaiah De Los Santos: Seahawks
- Tyler Maher: Seahawks

Titans vs Colts Picks

Titans (+3) vs Colts (-3) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Colts
- Isaiah De Los Santos: Colts
- Tyler Maher: Colts

Bears vs Giants Picks

Bears (+3.5) vs Giants (-3.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Bears
- Isaiah De Los Santos: Bears
- Tyler Maher: Giants

Jaguars vs Eagles Picks

Jaguars (+6.5) vs Eagles (-6.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Eagles
- Isaiah De Los Santos: Jaguars
- Tyler Maher: Eagles

Jets vs Steelers Picks

Jets (+3) vs Steelers (-3) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Steelers
- Isaiah De Los Santos: Steelers
- Tyler Maher: Steelers

Bills vs Ravens Picks

Bills (-3) vs Ravens (+3) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Ravens
- Isaiah De Los Santos: Ravens
- Tyler Maher: Bills

Chargers vs Texans Picks

Chargers (-5.5) vs Texans (+5.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Chargers
- Isaiah De Los Santos: Texans
- Tyler Maher: Chargers

Cardinals vs Panthers Picks

Cardinals (+1.5) vs Panthers (-1.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Cardinals
- Isaiah De Los Santos: Cardinals
- Tyler Maher: Cardinals

Patriots vs Packers Picks

Patriots (+9.5) vs Packers (-9.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Packers
- Isaiah De Los Santos: Packers
- Tyler Maher: Packers

Broncos vs Raiders Picks

Broncos (+2.5) vs Raiders (-2.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Broncos
- Isaiah De Los Santos: Broncos
- Tyler Maher: Broncos

Chiefs vs Buccaneers Picks

Chiefs (-1.5) vs Buccaneers (+1.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Chiefs
- Isaiah De Los Santos: Chiefs
- Tyler Maher: Chiefs

Rams vs 49ers Picks

Rams (+1.5) vs 49ers (-1.5) Betting Preview

Staff Picks (ATS):
- Taylor McKillop: Rams
- Isaiah De Los Santos: Rams
- Tyler Maher: Rams

Staff Records (ATS):
- Jason Schandl: 21-11 (65.63%)
- Taylor McKillop: 26-22 (54.17%)
- David Kaestle: 26-22 (54.17%)
- Isaiah De Los Santos: 25-22 (53.19%)
- Brian Giuffra: 8-8 (50.00%)
- Tyler Maher: 19-29 (39.58%)

Adam Taylor McKillop is not a FanDuel employee. In addition to providing DFS gameplay advice, Adam Taylor also participates in DFS contests on FanDuel using his personal account, username atmckillop. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.