Michigan State vs Penn State Prediction, Odds & Best Bet for Week 13 (Nittany Lions Cruise to Another Big Win)

Michigan State vs Penn State Week 12 Game Info

2022 NCAA College Football Game
Michigan State Spartans (5-6, 3-5 Big Ten) vs. No. 11 Penn State Nittany Lions (9-2, 6-2 Big Ten)
Date: Saturday, Nov. 26, 2022
Time: 4:00 p.m. ET
Venue: Beaver Stadium — University Park, PA
Coverage: FS1

Week 13 of the 2022 college football season includes a Big Ten battle between the Michigan State Spartans and No. 11 Penn State Nittany Lions. Michigan State is coming off a 39-31 loss to Indiana on Saturday. Running backs Jalen Berger and Elijah Collins combined for 226 yards and 2 scores.

Meanwhile, Penn State dominated Rutgers by a final score of 55-10 in Week 12. Freshman running back Kaytron Allen paced the offense with 117 yards and 1 touchdown on 11 carries. It was the Nittany Lions defense that shined, though, with two fumble recoveries taken back for touchdowns.

Michigan State vs Penn State Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: MSU: (+740) | PSU: (-1250)
Spread: MSU: +18.5 (-110) | PSU: -18.5 (-110)
Total: 53.5 — Over: (-108) | Under: (-112)

Penn State enters this contest as a heavy home favorite on the moneyline and the spread. This Big Ten clash also features a total of 53.5 points, which is about average compared to this week's college football projected totals.

Michigan State vs Penn State Prediction & Pick

Losing to Indiana as a 10-point home favorite was another bullet point in a long list of disappointing results for Michigan State this season. The Spartans once again could not buy a stop on defense, giving up 5.3 yards per play. They are now allowing 417.1 yards per game on the year (No. 97 in FBS).

Penn State is not the opponent any team wants to run into when it is having defensive issues. The Nittany Lions have scored at least 30 points in each of their last five games and are averaging 4.9 yards per carry (T-No. 29 in FBS). The backfield duo of Allen and Nick Singleton is growing stronger.

The last time Michigan State came to Beaver Stadium, it lost by 15 points. Give me Penn State here.

Final Score Prediction: Michigan State: 17 | Penn State: 38

Michigan State vs Penn State Betting Trends

- Michigan State is 6-3 straight up in its last nine games against Penn State.
- The total has hit the over in four of Michigan State's last six games.
- Penn State is 5-0 against the spread (ATS) in its last five games.
- The total has hit the over in 15 of Penn State's last 20 games against Michigan State.

Michigan State vs Penn State Best Bet

A big spread shouldn't scare bettors away from backing the home team. Seven of Penn State's nine wins on the year have been by at least 19 points, including each of its last four victories. Head coach James Franklin has his boys rolling and looking for revenge after a loss to Michigan State in 2021.

The Nittany Lions are 5-0 against the spread (ATS) over their last five games and 5-1 ATS in their last six games against a Big Ten opponent. On the other side, the Spartans are 2-6-1 ATS in their last nine games and 0-4-1 ATS in their last five games against a Big Ten East opponent. A blowout is coming.

Bet: Penn State Nittany Lions -18.5 (-110)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.