Lions vs Colts Prediction, Odds & Betting Trends for NFL Preseason Game on FanDuel Sportsbook (Aug 20)

Lions vs Colts Preseason Game Info

2022 NFL Preseason Game
Detroit Lions (0-1) vs. Indianapolis Colts (0-1)
Date: Saturday, August 20, 2022
Time: 1:00 p.m. ET
Venue: Lucas Oil Stadium — Indianapolis, IN

The Detroit Lions and Indianapolis Colts meet head-to-head in NFL preseason action on Saturday. Detroit couldn't hold on against the Atlanta Falcons last weekend, falling by a score of 27-23. Wide receiver Tom Kennedy dominated with 104 yards on 8 receptions as Detroit passed for 299 yards.

Meanwhile, the Colts surrendered a fourth quarter lead to the Buffalo Bills and lost by a score of 27-24. Quarterback Sam Ehlinger impressed by completing 10 of his 11 passes for 88 yards and a pair of touchdowns. Exciting rookie tight end Jelani Woods was one the receiving end of one of those TDs.

Lions vs Colts Odds & Spread

All NFL preseason betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: DET: (-120) | IND: (+100)
Spread: DET: -1.5 (-110) | IND: +1.5 (-110)
Total: 40.5 — Over: (-110) | Under: (-110)

The Lions enter this contest as a slight favorite on the moneyline and the spread. This 1 p.m. ET clash also features the second-highest total of Saturday's nine-game preseason slate.

Lions vs Colts Prediction & Pick

Both teams lost in a heartbreaking way last weekend and are looking to get momentum back on their side this time around. When it comes down to it, Detroit's offense is going to be the deciding factor here. They posted 393 total yards and converted 10 of 17 third down attempts against the Falcons.

The one thing that held the Lions back was a few messy turnovers. Head coach Dan Campbell is certainly going to have his players focusing on taking care of the football in practice this week. Going up against a Colts' defense that got picked apart late against the Bills, look for Detroit to excel.

Final Score Prediction: Lions: 27 | Colts: 21

Lions vs Colts Betting Trends

- Detroit is 7-3 against the spread (ATS) in its last 10 games.
- The total has hit the over in five of Detroit's last seven games.
- Indianapolis is 8-4 straight up in its last 12 games against Detroit.
- The total has hit the over in four of Indianapolis' last five games against Detroit.

Lions vs Colts Best Bet

All NFL preseason betting lines, odds and prop bets are available on FanDuel Sportsbook.

The Lions line up as a trendy moneyline bet in this one, but there is a ton of value in regards to the point total. Both of these teams took part in high-scoring games last weekend and allowed a combined 54 points on 682 yards of offense. Two struggling defenses means points will be scored.

On the other side of the football, Atlanta's rookie quarterback Desmond Ridder now has a taste of the NFL and will be looking to prove he can be the team's future starter. The same motivation can be found in Detroit's David Blough as he fights for the backup spot. Expect touchdowns galore here.

Bet: Over 40.5 Points (-110)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.