Colts vs Cowboys Prediction, Odds & Best Bet for Week 13 SNF (Dallas Piles Onto Indianapolis' Struggles)

Colts vs Cowboys Week 13 Game Info

2022 NFL Regular Season Game
Indianapolis Colts (4-7-1, 2-3-1 Away) vs. Dallas Cowboys (8-3, 5-1 Home)
Date: Sunday, Dec. 4, 2022
Time: 8:20 p.m. ET
Venue: AT&T Stadium— Arlington, TX
Coverage: NBC

Week 13 of the 2022 NFL season includes a Sunday Night Football showdown between the Indianapolis Colts and Dallas Cowboys. Jeff Saturday's lack of head coaching experience cost the Colts a shot at victory in Week 12, resulting in a 24-17 loss to the Pittsburgh Steelers on Monday.

Meanwhile, the Cowboys feasted on another win on Thanksgiving, defeating the New York Giants by a finals core of 28-20. Both aerial and ground attacks were working in Dallas' favor, highlighted by wideout CeeDee Lamb turning six receptions into 106 yards while running back Ezekiel Elliott racked up 92 rushing yards and a touchdown on 16 carries.

Colts vs Cowboys Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: IND: (+410) | DAL: (-550)
Spread: IND: +10.5 (-105) | DAL: -10.5 (-115)
Total: 43.5 —Over: (-110) | Under: (-110)

The Cowboys enter this contest as heavy favorites on the moneyline and spread on FanDuel Sportsbook's odds. This SNF matchup also features an over/under of 43.5, which is about average compared to the other Week 13 totals. 

Colts vs Cowboys Prediction & Pick

This showdown involves an absolute mismatch when it comes to offense. While the Colts have struggled to score the ball all season (15.8 PPG, No. 30), the Cowboys have no issues finding the end zone, scoring 40-plus points twice in the last four games while averaging 25.4 PPG (No. 7) throughout the campaign.

The Colts also have a turnover problem, especially as Matt Ryan is concerned. Indianapolis' underperforming offensive line has resulted in the former NFL MVP throwing out 11 picks (T-No. 2) while being sacked 32 times (No. 5). Considering how the Cowboys lead the NFL with 45 sacks, it's safe to say that Ryan will be under constant pressure, likely making even more mistakes.

Expect the Cowboys to dominate on both sides of the ball en route to their ninth win of the year.

Final Score Prediction: Cowboys: 26 | Colts: 14

Colts vs Cowboys Betting Trends

- Indianapolis is 1-6 straight up in its last seven road games against Dallas.
- Dallas is 7-3 against the spread (ATS) in its last 10 games.
- The total has hit the under in 14 of Indianapolis' last 17 games.
- The total has hit the under in four of Dallas' last five games against Indianapolis.

Colts vs Cowboys Best Bet

As far as best bets go, it's a good idea to back the Cowboys as -10.5 favorites. Is that a substantial spread? Yes, however, the Colts have lost three times on the road this season by an 18.7-point margin on average. On top of that, their minus-8.0 scoring margin on the road ranks fourth-worst in the NFL.

Meanwhile, the Cowboys are a respectable 4-2 ATS at home this season while picking up five of their last six wins by double-digit margins. In other words, don't be intimidated by the spread — back the Cowboys to cover.

Bet: Cowboys -10.5 (-115)

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.