Week 11 NFL Odds: Spreads, Moneylines, and Totals for Every Game

While Week 11 is headlined by a Super Bowl rematch on Monday Night Football, it kicks off with a key AFC North matchup.

Of course, Sunday is full of big-time games, as well, so Week 11 is primed to bring some great football.

Here are the NFL betting odds for each game in Week 11.

Chargers at Packers Week 11 Odds

• Spread: Chargers (-3)
• Los Angeles Chargers Moneyline: -158
• Green Bay Packers Moneyline: +134
• Total: 43.5

The Chargers couldn't outscore the Lions in Week 10 and lost 41-38 to fall to 4-5 on the season.

Green Bay nearly beat the Steelers -- but couldn't quite close it out -- and are now 3-6 on the year. Notably, they're 0-3 against AFC teams.

Chargers QB Justin Herbert has a 17-5 touchdown-to-interception ratio and has averaged 7.3 yards per attempt. Those numbers for Jordan Love are 14-10 and 6.7.

Titans at Jaguars Week 11 Odds

• Spread: Jaguars (-6.5)
• Tennessee Titans Moneyline: +260
• Jacksonville Jaguars Moneyline: -320
• Total: 40.5

Neither the Titans nor Jaguars scored even seven points in Week 10, and they combined for just 9 total points between them.

The Titans have now lost two straight games, and after a 238-yard, 4-touchdown, 0-interception debut for quarterback Will Levis, he has now gone for 262, 0, and 1 and 199, 0, and 1 in consecutive losses.

The Jaguars couldn't get things going against the 49ers in Week 10, and quarterback Trevor Lawrence was limited to 185 passing yards and 2 interceptions.

The Jaguars are expected to bounce back in Week 11.

Raiders at Dolphins Week 11 Odds

• Spread: Dolphins (-13.5)
• Las Vegas Raiders Moneyline: +610
• Miami Dolphins Moneyline: -900
• Total: 45.5

The Dolphins are coming off of a bye and have a lot to prove. Their 6-3 record looks good, yet their losses were to the Bills (48-20), Eagles (31-17), and Chiefs (21-14). We probably won't learn much about their ability to square up against elite teams this week, as they're big favorites against the Raiders.

This spread has lengthened a lot since open.

The Dolphins are getting RB De'Von Achane back for Week 11.

The Raiders held off the Jets 16-12 on Sunday Night Football in Week 10 but are only 1-4 on the road.

Cowboys at Panthers Week 11 Odds

• Spread: Cowboys (-10.5)
• Dallas Cowboys Moneyline: -590
• Carolina Panthers Moneyline: +430
• Total: 41.5

Dallas has ebbed and flowed this season but took care of the Giants in Week 10 by a score of 49-17. They're now 4-0 at home and 3-3 in the NFC but are expected to move to earn a win after the final buzzer in Week 11 against the Panthers.

Carolina has the mini-bye this week after a Thursday night game against the Bears, which they lost 16-13.

QB Bryce Young has averaged 4.7 yards per attempt over the past two weeks. That probably won't cut it against the Cowboys' defense.

Cardinals at Texans Week 11 Odds

• Spread: Texans (-5.5)
• Arizona Cardinals Moneyline: +190
• Houston Texans Moneyline: -230
• Total: 48.5

Arizona scored a last-second win thanks to some heroics from the returning Kyler Murray, whose passing numbers were modest in Week 10: 249 yards on 32 attempts. He ran 6 times for 33 yards and a touchdown, as well.

CJ Stroud and the Texans continue to be one of the league's most fun teams to watch. He and the Texans knocked off the Bengals 30-27. Stroud threw for 356 yards and a touchdown in that matchup. He now has three games with at least 350 yards in his career.

The injury report for this game features some key absences. Those include RB Dameon Pierce and WR Noah Brown for the Texans. Cardinals WR Michael Wilson has a shoulder injury, as well.

Steelers at Browns Week 11 Odds

• Spread: Browns (-2.5)
• Pittsburgh Steelers Moneyline: +116
• Cleveland Browns Moneyline: -136
• Total: 32.5

We get -- not one but -- two AFC North matchups this week. The Browns host the Steelers as moderate home favorites in a game with a very low total.

Both sides are 6-3.

The Steelers won the first game of this series 26-22 in Pittsburgh back in Week 2.

QB Kenny Pickett threw for 222 yards and a touchdown plus an interception on 30 attempts. George Pickens was the star. He had 127 yards and a touchdown.

Deshaun Watson threw 50 times for 236 yards with a touchdown and a pick while Jerome Ford took over for Nick Chubb and ran 16 times for 106 yards.

The Browns will start rookie Dorian Thompson-Robinson at quarterback for the second time this season. The total has plummeted.

Giants at Commanders Week 11 Odds

• Spread: Commanders (-9.5)
• New York Giants Moneyline: +360
• Washington Commanders Moneyline: -460
• Total: 37.5

These two teams are representing the bottom half of the NFC East, and the Giants' win in their first matchup could prove costly for the now 4-6 Commanders.

New York won 14-7 while holding Washington to 1-for-15 on third down conversions. Washington also racked up 10 penalties (the Giants had 4).

Washington is expected to get their win back and move to 5-6 on the year based on a big spread.

RB Antonio Gibson is doubtful.

Bears at Lions Week 11 Odds

• Spread: Lions (-7.5)
• Chicago Bears Moneyline: +315
• Detroit Lions Moneyline: -400
• Total: 47.5

The Bears bring a 3-7 overall record and 1-4 road record into a matchup with the red hot Detroit Lions (7-2 on the year), who sit atop the NFC North.

Despite the divisional matchup here, the two haven't yet met and will play one another again in Week 14.

QB Jared Goff has thrown for at least 272 yards in four straight games, and the team's two-back backfield with David Montgomery and Jahmyr Gibbs is looking quite formidable.

Oh, and Amon-Ra St. Brown has secured at least 102 receiving yards in four straight games.

Justin Fields will start for Chicago.

Buccaneers at 49ers Week 11 Odds

• Spread: 49ers (-11.5)
• Tampa Bay Buccaneers Moneyline: +480
• San Francisco 49ers Moneyline: -650
• Total: 41.5

There's another big spread on the board, and this one favors the 49ers at home against the Bucs, who finally snapped a losing streak thanks to a 20-6 win over the Titans in Week 10.

The 49ers had a three-game losing streak of their own but ended it with a dominant 34-3 win over the Jaguars on the road.

Brock Purdy has thrown for 272, 365, and 296 yards over the past three games for the 49ers, and TE George Kittle has consecutive 100-yard games.

Jets at Bills Week 11 Odds

• Spread: Bills (-7)
• New York Jets Moneyline: +270
• Buffalo Bills Moneyline: -335
• Total: 40

The first matchup between the Jets and Bills had plenty of storylines, including the season-ending injury for quarterback Aaron Rodgers and a scrappy comeback win for the Jets at home in overtime.

This time around, though, the Bills are big favorites.

They're 5-4 overall yet 4-1 at home. It's worth noting that they're only 1-2 in the division, so divisional wins are needed as they look to chase down the Dolphins (6-3).

Jets WR Garrett Wilson is dealing with an elbow injury.

Seahawks at Rams Week 11 Odds

• Spread: Seahawks (-1.5)
• Seattle Seahawks Moneyline: +112
• Los Angeles Rams Moneyline: -132
• Total: 46.5

The Seahawks are 6-3 despite a season-long point differential of -1, which really means they should be 5-4 or 4-5, but they're finding ways to get it done -- especially at home where they're 4-1. They're also 5-1 in the NFC.

The Rams are just 3-6 overall and 1-3 at home.

With all that said, the Rams' lone home win this season -- and the Seahawks' lone NFC loss -- came back in Week 1.

LA won 30-13 while Puka Nacua broke out for 10 catches and 119 yards.

QB Matthew Stafford is expected to return in Week 11.

The total has gone up since earlier in the week.

Seahawks WR Tyler Lockett is questionable.

Vikings at Broncos Week 11 Odds

• Spread: Broncos (-3)
• Minnesota Vikings Moneyline: +124
• Denver Broncos Moneyline: -146
• Total: 41

A low total is waiting for us on Sunday Night Football again in Week 11.

The Vikings are 6-4 on the year with a very impressive 4-1 road record and 6-2 conference record. Minnesota has won five straight games, including two games with Josh Dobbs commanding the offense. TE TJ Hockenson has 69 and 134 yards in two games played primarily by Dobbs.

The Broncos are in primetime again after a Monday Night Football matchup with the Bills, which they won 24-22.

Eagles at Chiefs Week 11 Odds

• Spread: Chiefs (-2.5)
• Philadelphia Eagles Moneyline: +128
• Kansas City Chiefs Moneyline: -152
• Total: 45.5

A rematch of Super Bowl LVII is set for Monday Night Football in Week 11.

The 7-2 Chiefs and 8-1 Eagles will each be coming off of a bye to square up in a highly anticipated game.

Kansas City has a 4-1 home record that they'll look to protect against an Eagles team that travels well.

A high total and tight spread is all we could ask for after some of the primetime matchups we've had in recent weeks.

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