Vanderbilt vs Missouri College Basketball Prediction, Odds, Picks, Best Bets for Feb. 18

SEC action on Wednesday will see the the No. 19 Vanderbilt Commodores (21-4, 8-4 SEC) visit the Missouri Tigers (17-8, 7-5 SEC) at Mizzou Arena, tipping off at 9 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Vanderbilt vs. Missouri Game Info and Odds

• Game day: Wednesday, February 18, 2026
• Game time: 9 p.m. ET
• TV channel: SEC Network
• Location: Columbia, Missouri
• Arena: Mizzou Arena

Take a look at some betting insights for Vanderbilt (-3.5) versus Missouri on Wednesday. The over/under has been set at 154.5 points for this game.

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Vanderbilt vs. Missouri: ATS Betting Stats and Trends

• Vanderbilt has won 14 games against the spread this season, while failing to cover 11 times.
• Missouri is 10-15-0 ATS this season.
• When the spread is set as 3.5 or more this season, Vanderbilt (13-9) covers a higher percentage of those games when it is the favorite (59.1%) than Missouri (3-3) does as the underdog (50%).
• The Commodores have covered the spread in a lower percentage of their home games than away games. They have covered seven times in 14 games at home, and they've covered five times in eight games on the road.
• This season, the Tigers are 6-9-0 at home against the spread (.400 winning percentage). On the road, they are 4-4-0 ATS (.500).
• Vanderbilt has covered the spread six times in 12 conference games.
• Missouri has beaten the spread five times in 12 SEC games.

Vanderbilt vs. Missouri: Moneyline Betting Stats

• Vanderbilt has been victorious in 16, or 88.9%, of the 18 contests it has been chosen as moneyline favorites in this season.
• This season, the Commodores have been victorious 16 times in 18 chances when named as a favorite of at least -176 or better on the moneyline.
• Missouri has been the underdog on the moneyline nine total times this season. Missouri has gone 4-5 in those games.
• The Tigers have gone 3-3 when they have played as a moneyline underdog with odds of +146 or longer (50%).
• The moneyline set for this matchup implies Vanderbilt has a 63.8% chance of coming away with a victory in the contest.

Vanderbilt vs. Missouri Head-to-Head Comparison

• Vanderbilt's +370 scoring differential (outscoring opponents by 14.8 points per game) is a result of scoring 88.4 points per game (12th in college basketball) while allowing 73.6 per contest (175th in college basketball).
• Tyler's team-leading 18.3 points per game ranks 82nd in the nation.
• Missouri has a +143 scoring differential, topping opponents by 5.7 points per game. It is putting up 80 points per game, 98th in college basketball, and is allowing 74.3 per contest to rank 196th in college basketball.
• Mark Mitchell's team-leading 17.2 points per game rank him 143rd in college basketball.
• The Commodores prevail in the rebound battle by an average of 2.4 boards. They are pulling down 33.1 rebounds per game (124th in college basketball) compared to their opponents' 30.7 per contest.
• Devin averages 6.9 rebounds per game (ranking 176th in college basketball) to lead the Commodores.
• The 33.2 rebounds per game the Tigers accumulate rank 117th in college basketball, 4.7 more than the 28.5 their opponents grab.
• Mitchell averages 5.6 rebounds per game (382nd in college basketball) to lead the Tigers.
• Vanderbilt's 109.7 points per 100 possessions on offense rank seventh in college basketball, and the 91.3 points it allows per 100 possessions rank 89th in college basketball.
• The Tigers rank 75th in college basketball averaging 102.5 points per 100 possessions on offense, and defensively are 202nd, allowing 95.2 points per 100 possessions.

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