USC vs Oregon College Basketball Prediction, Odds, Picks, Best Bets for Dec. 2

The USC Trojans (7-0, 0-0 Big Ten) hope to extend a seven-game winning streak when they visit the Oregon Ducks (4-3, 0-0 Big Ten) on December 2, 2025 at Matthew Knight Arena.

Before you place your bet on this matchup at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

USC vs. Oregon Game Info and Odds

• Game day: Tuesday, December 2, 2025
• Game time: 10 p.m. ET
• TV channel: Fox Sports 1
• Location: Eugene, Oregon
• Arena: Matthew Knight Arena

USC vs. Oregon Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: USC win (53.5%)

Read the betting insights and trends below before making a bet on Tuesday's USC-Oregon spread (USC -1.5) or total (155.5 points).

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USC vs. Oregon: ATS Betting Stats and Trends

• USC has covered four times in seven matchups with a spread this season.
• Oregon is winless against the spread this season (0-7-0).
• USC covers the spread when it is a 1.5-point favorite or more 57.1% of the time. That's more often than Oregon covers as an underdog of 1.5 or more (never covered this season).
• Against the spread last season, the Trojans played better at home, covering eight times in 19 home games, and four times in 10 road games.
• In 2024-25 against the spread, the Ducks had a lower winning percentage at home (.375, 6-10-0 record) than away (.455, 5-6-0).

USC vs. Oregon: Moneyline Betting Stats

• USC has yet to lose any of the seven games it has been chosen as the moneyline favorite in this season.
• The Trojans have been a -137 moneyline favorite on seven occasions this season and won every game.
• Oregon has been listed as the moneyline underdog only two other times so far this season, and it lost both games.
• The Ducks have played as a moneyline underdog of +114 or longer in only two games this season, which they lost both.
• USC has an implied victory probability of 57.8% according to the moneyline set for this matchup.

USC vs. Oregon Head-to-Head Comparison

• USC's +100 scoring differential (outscoring opponents by 14.3 points per game) is a result of scoring 91.9 points per game (20th in college basketball) while allowing 77.6 per outing (263rd in college basketball).
• Rodney Rice ranks 31st in college basketball with a team-leading 20.3 points per game.
• Oregon scores 73.7 points per game (268th in college basketball) and gives up 74.7 (214th in college basketball) for a -7 scoring differential overall.
• Nathan Bittle's team-leading 16.3 points per game rank him 191st in the nation.
• The Trojans grab 36.1 rebounds per game (85th in college basketball) while conceding 32.1 per contest to their opponents. They outrebound opponents by four boards per game.
• Jacob Cofie's 7.6 rebounds per game lead the Trojans and rank 115th in college basketball play.
• The 35.9 rebounds per game the Ducks accumulate rank 96th in college basketball, 5.3 more than the 30.6 their opponents grab.
• Bittle tops the Ducks with 7.8 rebounds per game (101st in college basketball).
• USC puts up 105.5 points per 100 possessions (60th in college basketball), while allowing 89.1 points per 100 possessions (136th in college basketball).
• The Ducks rank 278th in college basketball with 91.8 points scored per 100 possessions, and 217th defensively with 93.1 points conceded per 100 possessions.

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