Yankees vs Guardians Prediction, Odds, Betting Trends & Probable Pitchers for ALDS Game 4 MLB Playoffs

Yankees vs Guardians Game 4 Info

2022 MLB Playoffs — ALDS Game 4 (CLE Leads 2-1)
No. 2 New York Yankees (99-63, 42-39 Away) vs. No. 3 Cleveland Guardians (92-70, 46-35 Home)
Date: Sunday, October 16, 2022
Time: 7:07 p.m. ET
Venue: Progressive Field — Cleveland, OH
Coverage: TBS

The ALDS continues on Sunday with Game 4 between the No. 2 New York Yankees and No. 3 Cleveland Guardians. The Guardians are riding high after Saturday's walk-off win, and now are just one victory away from moving on to the ALCS.

The Yankees, meanwhile, will look to break the trend of higher seeds being upset in the Divisional Round and force a Game 5 in New York. They'll need to steal one on the road, or their dominant 2022 season will be over.

Yankees vs Guardians Odds & Spread

All MLB Postseason betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: NYY: (-166) | CLE: (+140)
Spread: NYY: -1.5 (+104) | CLE: +1.5 (-125)
Total: 6.5 — Over: (-122) | Under: (+100)

The Yankees enter this contest as a slight road favorite on the moneyline and spread. They are -166 on the moneyline and own +104 odds to cover the 1.5-run spread. The over/under on this matchup features 6.5 runs, with -122 on the over and +100 on the under.

Yankees vs Guardians Prediction & Pick

The Yankees will turn to Gerrit Cole on the mound once again this series, and that could be bad news for the Guardians. Cole has had Cleveland's number all season, going 2-0 against this team in the regular season with just a combined 2 earned runs and 7 hits allowed. That success translated to Game 1 of this series, where Cole picked up New York's only win by holding the Guardians to 4 hits and just 1 run in 6.1 innings.

Cal Quantrill, meanwhile, failed to outdo Cole to kick off the ALDS. He only lasted 5.0 innings, giving up 3 ER (including two home runs) while throwing 84 pitches.

Cleveland needed a 3-run comeback to win on Saturday in a game New York should've won. Look for the Yankees to respond with their backs up against the wall and extend this series.

Final Score Prediction: Yankees: 4 | Guardians: 2

Yankees vs Guardians Probable Starting Pitchers

The New York Yankees will look to Gerrit Cole (13-8 3.50 ERA) in Game 4 and the Cleveland Guardians hand the ball to Cal Quantrill (15-5, 3.38 ERA).

Yankees vs Guardians Betting Trends

- The Yankees are 1-5 against the spread (ATS) in their last six games.
- The Yankees are 6-3 in their last nine games in Cleveland.
- Cleveland is 14-7 ATS in its last 21 games.
- The total has hit the over in seven of Cleveland's last nine home games.

Isaiah De Los Santos is not a FanDuel employee. In addition to providing DFS gameplay advice, Isaiah De Los Santos also participates in DFS contests on FanDuel using his personal account, username zayyy05328. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.