Steelers vs Bills Expert Picks & Predictions for Week 5 NFL Game

The 2022 NFL season is finally here and the Week 5 schedule is chock full of exciting showdowns. The action includes an intriguing matchup between the Pittsburgh Steelers and Buffalo Bills.

The Steelers haven't been able to get much going this year, losing three games in a row following their 24-20 loss to the New York Jets. Meanwhile, the Bills bounced back from their Week 3 loss by defeating the Baltimore Ravens, 23-20.

Can the Steelers do the unthinkable by scoring an upset win at Highmark Stadium? Or will Buffalo make an example of the 'Black and Yellow' in front of Bills Mafia?

Here's what projection models and experts across the industry have to say about the Steelers vs Bills Week 5 matchup.

Steelers vs Bills Projections

ESPN FPI: Bills (85.9%)
numberFire: Bills (84.3%)
FiveThirtyEight: Bills (88%)
Betting Favorite: Bills (-14)

Projected Winner: Bills (4)

Steelers vs Bills Expert Picks

ESPN Experts: Bills (7)
Sports Illustrated Experts: TBD
CBS Sports Experts: Bills (5), Steelers (2)

Expert Totals: Bills (12), Steelers (2)

When it comes to projections, the four highlighted sources are all backing the Bills to win. While the experts' assessment isn't unanimous, 85.7% of them also side with a Buffalo victory. 

As far as a Steelers upset goes, their best shot at winning comes in at 15.7% on numberFire, so things aren't looking promising for Pittsburgh.

Although you can never say never in professional sports, it's hard picturing the Bills losing this one.

Devon Platana is not a FanDuel employee. In addition to providing DFS gameplay advice, Devon Platana also participates in DFS contests on FanDuel using his personal account, username PepeSilvia0. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.