Patriots vs Vikings Prediction, Odds & Best Bets for Thanksgiving (New England's Defense Shows Up on Thanksgiving)

Patriots vs Vikings Week 12 Game Info

2022 NFL Regular Season — Week 12
New England Patriots (6-4, 3-2 Away) vs. Minnesota Vikings (8-2, 4-1 Home)
Date: Thursday, Nov. 24, 2022
Time: 8:20 p.m. ET
Venue: U.S. Bank Stadium — Minneapolis, MN
Coverage: NBC

A trio of NFL games on Thanksgiving day concludes with an exciting matchup between the New England Patriots and Minnesota Vikings. The Patriots edged the New York Jets by a score of 10-3 in Week 11. Rookie Marcus Jones' punt return touchdown late in the fourth quarter sealed the victory.

Meanwhile, the Vikings saw their seven-game winning streak snapped in a disappointing 40-3 loss to the Dallas Cowboys on Sunday. Quarterback Kirk Cousins completed just 12 of his 23 pass attempts for a season-low 105 yards. Minnesota's defense was gashed for a whopping 6.5 yards per play.

Patriots vs Vikings Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: NE: (+132) | MIN: (-156)
Spread: NE: +3 (-110) | MIN: -3 (-110)
Total: 41.5 — Over: (-118) | Under: (-104)

The Vikings enter this contest as a small home favorite on the moneyline and the spread. This Thanksgiving clash also features one of the lower totals on the Week 12 slate at 41.5 points.

Patriots vs Vikings Prediction & Pick

Talk about two teams entering a game with completely different momentums. New England is back in the AFC playoff picture following its Week 11 win and ranks as the second-best scoring defense in the NFL (16.9 points per game allowed). Head coach Bill Belichick is making all of the right decisions.

On the other side, The Vikings' struggles on defense finally caught up to them. Minnesota is giving up a red zone scoring percentage of 71.4% (No. 32 in NFL) and a third down conversion percentage of 41.5% (No. 23 in NFL). Not being able to get off the field is deleting chances for the offense to score.

New England is 5-0 straight up in its last five games against Minnesota, so I find myself liking an upset here.

Final Score Prediction: Patriots: 20 | Vikings: 17

Patriots vs Vikings Betting Trends

- New England is 6-1 against the spread (ATS) in its last seven games.
- The total has hit the under in 12 of New England's last 18 away games.
- Minnesota is 5-1 straight up in its last six home games.
- The total has hit the under in six of Minnesota's last seven games against New England.

Patriots vs Vikings Best Bet

The Patriots have quietly been one of the best teams in the NFL over the last two months. They are 5-2 straight up in their last seven games and only one of those two losses came by more than a field goal. New England is an impressive 6-1 against the spread (ATS) during that same stretch of games.

Cousins has little experience playing against New England, posting an 0-2 record to go along with a touchdown to interception ratio of 2:3. The veteran QB has never found much success on primetime, though. Cousins owns a subpar record of 6-9 with Minnesota in games that kick off past 7 p.m. ET.

Bet: New England Patriots +3 (-110)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.