Patriots vs Bills Point Spread, Over/Under, Moneyline and Betting Trends for AFC Wild Card Game on FanDuel

Updated: Sep 10, 5:00pm UTC

The NFL's Super Wild Card Weekend slate of games includes an AFC Wild Card showdown between the New England Patriots and Buffalo Bills.

Here's everything you need to know before placing your bet for this game on FanDuel Sportsbook.

Patriots vs Bills Point Spread

The Bills are 4-point home favorites against the Patriots. Buffalo is -114 to cover the spread, while New England is -106 to cover as a 4-point underdog.

Patriots vs Bills Over/Under

The over/under for the Patriots vs Bills AFC Wild Card matchup is set at 44, with -110 odds on the over and -110 odds on the under.

Patriots vs Bills Moneyline

The Patriots vs Bills moneyline has Buffalo as a -205 favorite, while New England is a +172 underdog on the road.

Patriots vs Bills Betting Trends

- Buffalo is 1-1 in two previous head-to-head matchups with New England during the 2021-22 NFL regular season.
- Buffalo defeated New England, 33-21, in the most recent meeting between these two teams in Week 16 of the NFL season.
- New England is 8-3 against the spread (ATS) in its last 11 games.
- The total has hit the over in nine of New England's last 13 games.
- Buffalo is 2-2-2 ATS in its last six home games.
- The total has hit the under in five of Buffalo's last seven home games.

Patriots vs Bills Prediction

All NFL predictions and picks are from numberFire's projection model.
Prediction: Buffalo Bills wins (70.9%)

Patriots vs Bills Odds

All NFL playoff betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: NE: (+172) | BUF: (-205)
Spread: NE: +4 (-106) | BUF: -4 (-114)
Total: 44 — Over: (-110) | Under: (-110)
Odds to Win Super Bowl LVI: NE: (+2200) | BUF: (+750)

Devon Platana is not a FanDuel employee. The views expressed in his articles are the author's alone and do not necessarily reflect the views of FanDuel.