Louisville vs Kentucky Prediction, Odds & Best Bet for Week 13 (Wildcats' Defense Continues Dominance at Home)

Louisville vs Kentucky Week 12 Game Info

2022 NCAA College Football Game
Louisville Cardinals (7-4) vs. Kentucky Wildcats (6-5)
Date: Saturday, Nov. 26, 2022
Time: 3:00 p.m. ET
Venue: Kroger Field — Lexington, KY
Coverage: SEC Network

Week 13 of the 2022 college football season includes an in-state rivalry battle between the Louisville Cardinals and Kentucky Wildcats. Louisville pulled off a 25-10 home win over NC State its last time out thanks to running back Jawhar Jordan. The sophomore racked up 118 yards and 2 touchdowns.

Meanwhile, Kentucky fell short against Georgia is a 16-6 loss in Week 12. The Wildcats averaged just 3.6 yards per carry on the ground and could only post one scoring drive late in the fourth quarter. Quarterback Will Levis finished the game 20-of-31 with 206 yards, 1 touchdown and 1 interception.

Louisville vs Kentucky Odds & Spread

All NCAAF betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: LOUIS: (+142) | UK: (-172)
Spread: LOUIS: +3.5 (-118) | UK: -3.5 (-104)
Total: 43.5 — Over: (-110) | Under: (-110)

Kentucky enters this contest as a small home favorite on the moneyline and the spread. This Saturday clash also features a total of 43.5 points, which is below average compared to this week's college football projected totals.

Louisville vs Kentucky Prediction & Pick

These in-state rivals that have met head-to-head in every season since 1994. The Cardinals and Wildcats are set to compete for the Governor's Cup again on Saturday, but only one team enters with an edge. Kentucky has taken down Louisville by at least 31 points in each of the last three matchups.

In 2021, Levis torched the Cardinals by logging 113 rushing yards to go along with 4 touchdowns by the time the final whistle blew. He should be able to find similar success this time around as Louisville has given up an average of 163.8 rushing yards on 4.5 yards per carry across five 2022 away games.

Final Score Prediction: Louisville: 17 | Kentucky: 23

Louisville vs Kentucky Betting Trends

- Louisville is 5-1 against the spread (ATS) in its last six games.
- The total has hit the under in four of Louisville's last five games.
- Kentucky is 4-1 straight up in its last five games against Louisville.
- The total has hit the under in six of Kentucky's last seven home games.

Louisville vs Kentucky Best Bet

Bettors that have backed the under in Kentucky games this season have to be happy with the results, as it's a wager that has cashed in each of the Wildcat's last seven games. The total has also hit the under in six of Kentucky's last seven home games as well as in four of Louisville's last five games.

It all comes down to head coach Mark Stoops' defense. Kentucky is allowing only 21.6 points on 334.3 yards per game, both of which rank among the top-30 team averages in the nation. The Wildcats give up just 5.0 yards per play at Kroger Field, too. This game screams low-scoring battle.

Bet: Under 43.5 Points (-110)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel. 

Game odds refresh periodically and are subject to change.