Buccaneers vs Saints Prediction, Odds & Betting Trends for NFL Week 2 Game on FanDuel Sportsbook

Buccaneers vs Saints Week 2 Game Info

2022 NFL Regular Season — Week 2 Game
Tampa Bay Buccaneers (1-0, 1-0 Away) vs. New Orleans Saints (1-0, 0-0 Home)
Date: Sunday, September 18, 2022
Time: 1:00 p.m. ET
Venue: Caesars Superdome — New Orleans, LA
Coverage: FOX

The Tampa Bay Buccaneers will look to cement a lead atop the NFC South when they visit the New Orleans Saints in Week 2 NFL action. Tampa Bay picked apart the Dallas Cowboys with ease in Week 1, emerging victorious by a score of 19-3. Linebacker Devin White racked up 2.0 sacks in the game.

Meanwhile, quarterback Jameis Winston guided the Saints to a fourth-quarter comeback win over the Atlanta Falcons. New Orleans earned a 27-26 win thanks to wide receiver Michael Thomas' pair of touchdowns. Kicker Will Lutz nailed a game-winning 51-yard field goal with only 20 seconds to go.

Buccaneers vs Saints Odds & Spread

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: TB: (-146) | NO: (+124)
Spread: TB: -2.5 (-120) | NO: +2.5 (-102)
Total: 43.5 — Over: (-110) | Under: (-110)

Updated (Sunday, Sept. 18, 12:30 p.m. EST): Updated odds were provided from FanDuel Sportsbook. The Saints saw a marginal improvement in their moneyline odds, down to +124. The over/under point total also fell from 45.5 points to just 43.5 on Sunday.

The Buccaneers enter this contest as a small favorite on the moneyline and the spread. This 1 p.m. ET clash also features one of the higher projected totals (45.5) on the NFL Week 2 slate.

Buccaneers vs Saints Prediction & Pick

It's no secret that the Saints have dominated this head-to-head series as of late. New Orleans took Tampa Bay down twice in 2021 after splitting the season series in 2020 as well. This defense has gotten the better of quarterback Tom Brady, but the GOAT has a solid defense backing him up, too.

The Bucs did not let the Cowboys get anything going on offense in Week 1 and allowed a minuscule 3.8 yards per play. They also racked up four sacks and were constantly in the backfield. Not letting Winston get comfortable in the pocket will be the key to pulling off a crucial divisional win on the road.

Final Score Prediction: Buccaneers: 27 | Saints: 17

Buccaneers vs Saints Betting Trends

- Tampa Bay is 1-7 straight up in its last eight games against New Orleans.
- The total has hit the over in seven of Tampa Bay's last nine games in September.
- New Orleans is 7-1 against the spread (ATS) in its last eight games against Tampa Bay.
- The total has hit the under in four of New Orleans' last five home games.

Buccaneers vs Saints Best Bet

All NFL betting lines, odds and prop bets are available on FanDuel Sportsbook.

Sticking with a bet on the spread is the best choice here as the previous four games in this series have been split in terms of hitting the over or the under. A motivated Brady is a scary sight and that is exactly what we have here. Seeing him lose three straight games to one opponent would be a shock.

The Buccaneers have the personnel to grind the Saints down in this game. Running back Leonard Fournette logged 127 yards on 21 carries in Week 1 and was not utilized properly in two matchups against the Saints in 2021. Expect that to change on Sunday in a close victory for Tampa Bay.

Bet: Buccaneers Win by 1-13 Points (+150)

Larry Rupp is not a FanDuel employee. In addition to providing DFS gameplay advice, Larry Rupp also participates in DFS contests on FanDuel using his personal account, username phillyfan424. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.