Bills vs Chiefs Opening Odds, Betting Lines & Prediction for Week 6 Game on FanDuel Sportsbook

Week 5 NFL action is underway, but FanDuel Sportsbook has already released NFL odds and lines for Week 6, giving us an early preview of next week's slate.

Week 6's late afternoon slate sets up an exciting AFC clash between two Super Bowl contenders in the Buffalo Bills and Kansas City Chiefs.

Bills vs Chiefs Odds & Lines Week 6

All NFL betting lines, odds and prop bets are from FanDuel Sportsbook.
Moneyline: BUF: (-106) | KC: (-110)
Spread: BUF: +1 (-112) | KC: -1 (-108)
Total: N/A — Over: (N/A) | Under: (N/A)

The Chiefs welcome the Bills back to Arrowhead Stadium after breaking their hearts in overtime during last year's playoffs. Kansas City is a slight home favorite on the spread and moneyline. While the total hasn't been released yet, this game will likely have the highest total on the Week 6 slate.

Bills vs Chiefs Prediction Week 6

Early NFL predictions and picks are from ESPN's Football Power Index (FPI).
Bills: 37.8% to win
Chiefs: 61.8% to win

I'm surprised to see the Chiefs so highly rated on ESPN's FPI, as this game could really go either way. Buffalo has a much better defense than Kansas City and the Bills' offense is arguably just as good as the Chiefs', if not better. I think Buffalo has the superior team this year and will be extra motivated to avenge last year's postseason loss, so I recommend that you Bet Bills ML (-106).

Game odds refresh periodically and are subject to change.