Astros vs White Sox Prediction, Odds & Best Bet for May 13 (Houston Scores Road Win)

The Houston Astros (20-18) will visit the Chicago White Sox (13-27) for the middle game of their three-game set on Saturday night. The Astros came away with a 5-1 win in the first game of the series on Friday.

Can the Astros grab the series win tonight, or will Chicago tie things up heading into Sunday?

Astros vs White Sox Game Info

• Date: Saturday, May 13, 2023
• Time: 7:15 p.m. ET
• Venue: Guaranteed Rate Field -- Chicago, IL
• Coverage: FOX

Houston hasn't been the powerhouse team out of the gate it has been the last few years, but still remains a couple of games above .500 and just three games back of the AL West lead.

Chicago, meanwhile, is having a horrendous season -- the type of season that might trigger a rebuild for this once promising and talented young group.

Astros vs White Sox Odds & Spread

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: HOU: (+112) | CWS: (-132)
• Spread: HOU: +1.5 (-188) | CWS: -1.5 (+155)
• Total: 8.5 -- Over: (-114) | Under: (-106)

Despite the White Sox's struggles overall, Chicago comes in as the home favorite in this one. The over/under is set at 8.5 with the over being favored at -114.

Astros vs White Sox Betting Trends

• The total has hit the under in four of Houston's last five games.
• Houston is 5-2 in its last seven games against the White Sox.
• The White Sox are 1-4 in their last five games.
• The total has hit the over in four of the White Sox's last six games against Houston.

Astros vs White Sox Prediction & Pick

Chicago starter Dylan Cease's last start against Houston was on Opening Day this season and he pitched well, surrendering just one run in 6 1/3 innings pitched on the way to a 3-2 White Sox win.

However, things have gone south for Cease since then. He has now given up at least three runs in his last four starts. Simply put, he has lost it.

I don't expect this talented Astros lineup to be the one that allows Cease to find his groove again. This could be a quick outing for Cease and a win for Houston.

Final Score Prediction: Astros: 6 | White Sox: 3

Astros vs White Sox Best Bet

Cease has still been striking people out even amidst his struggles, but not to the tune that his 6.5 strikeout prop suggests. Cease has failed to reach seven strikeouts in six consecutive starts now and has only completed more than five innings once in that timeframe.

With the expectation that Cease's struggles will continue against Houston, he might not be in the game long enough to reach this total.

Bet: Dylan Cease Under 6.5 Strikeouts (-148)

David Kaestle is not a FanDuel employee. In addition to providing DFS gameplay advice, David also participates in DFS contests on FanDuel using his personal account, username davekaestle. While the strategies and player selections recommended in his articles are his personal views, he may deploy different strategies and player selections when entering contests with his personal account. The views expressed in their articles are the author's alone and do not necessarily reflect the views of FanDuel.

Game odds refresh periodically and are subject to change.