Reds vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for May 24

Odds updated as of 10:12 p.m.

The Cincinnati Reds will face the St. Louis Cardinals in MLB action on Sunday.

All the information you need to make smart wagers on this matchup at FanDuel Sportsbook can be found below. Check out all of the latest MLB betting lines here.

Reds vs Cardinals Game Info

• Cincinnati Reds (26-25) vs. St. Louis Cardinals (29-21)
• Date: Sunday, May 24, 2026
• Time: 1:40 p.m. ET
• Venue: Great American Ball Park -- Cincinnati, Ohio
• Coverage: Reds.TV and Cardinals.TV

Reds vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: CIN: (-116) | STL: (-102)
• Spread: CIN: +1.5 (-192) | STL: -1.5 (+158)
• Total: 9.5 -- Over: (-105) | Under: (-115)

Reds vs Cardinals Probable Starting Pitchers

Probable Pitchers: Brady Singer (Reds) - 2-4, 6.26 ERA vs Matthew Liberatore (Cardinals) - 2-2, 4.70 ERA

The probable starters are Brady Singer (2-4) for the Reds and Matthew Liberatore (2-2) for the Cardinals. Singer and his team have a record of 6-3-0 against the spread when he starts. Singer's team is 1-1 this season when he starts and they're favored on the moneyline. When Liberatore starts, the Cardinals are 6-4-0 against the spread. The Cardinals are 6-3 in Liberatore's nine starts this season that they were the moneyline underdog.

Reds vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Reds win (58.7%)

Reds vs Cardinals Moneyline

• Looking at the moneyline for Cardinals-Reds, St. Louis is the underdog at -102, and Cincinnati is -116 playing at home.

Reds vs Cardinals Spread

• The Cardinals are 1.5-run favorites against the spread for this matchup with the Reds. The Cardinals are +158 to cover, while the Reds are -192 to cover as a 1.5-run underdog on the runline.

Reds vs Cardinals Over/Under

• The over/under for the Reds versus Cardinals game on May 24 has been set at 9.5, with -105 odds on the over and -115 odds on the under.

Bet on Cincinnati Reds vs. St. Louis Cardinals on FanDuel today!

Reds vs Cardinals Betting Trends

• The Reds have been favorites in 17 games this season and have come away with the win nine times (52.9%) in those contests.
• This season Cincinnati has come away with a win seven times in 13 chances when named as a favorite of at least -116 on the moneyline.
• Contests with the Reds have gone over the total set by oddsmakers in 30 of 49 chances this season.
• The Reds are 29-20-0 against the spread in their 49 games with a line set by sportsbooks this season.
• The Cardinals have been the moneyline underdog 41 total times this season. They've finished 24-17 in those games.
• St. Louis has gone 20-17 when playing as a moneyline underdog with odds of -102 or longer (54.1%).
• In the 49 games bookmakers have set an over/under for the Cardinals, they have combined with opponents to go over the total 21 times (21-24-4).
• The Cardinals have gone 30-19-0 ATS this season.

Reds Player Leaders

• Sal Stewart is batting .259 with nine doubles, 12 home runs and 27 walks. He has an on-base percentage of .347 and a slugging percentage of .492.
• Among all qualified batters in the majors, he ranks 70th in batting average, 59th in on-base percentage, and 29th in slugging.
• Elly De La Cruz leads Cincinnati with 58 hits and an OBP of .350, plus a team-best slugging percentage of .515. He's batting .284.
• He is 34th in batting average, 55th in on-base percentage and 20th in slugging in the major leagues.
• Spencer Steer is batting .270 with a .443 slugging percentage and 18 RBI this year.
• JJ Bleday is batting .288 with a .396 OBP and 20 RBI for Cincinnati this season.

Cardinals Player Leaders

• Jordan Walker is leading the Cardinals with 55 hits. He's batting .293 and slugging .569 with an on-base percentage of .362.
• Including all the qualified hitters in the big leagues, his batting average ranks 20th, his on-base percentage ranks 38th, and he is sixth in slugging.
• Alec Burleson paces his team with a .468 slugging percentage. He has a batting average of .295 with an on-base percentage of .364.
• His batting average is 17th among all qualified players, his on-base percentage is 35th, and he is 44th in slugging.
• Ivan Herrera a has .395 on-base percentage to lead the Cardinals.
• JJ Wetherholt is batting .238 with five doubles, nine home runs and 26 walks.

Reds vs Cardinals Head to Head

• 5/23/2026: 8-1 STL (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 9/17/2025: 6-2 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 9/16/2025: 3-0 STL (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -124, Underdog Moneyline: +106)
• 9/15/2025: 11-6 CIN (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 8/31/2025: 7-4 CIN (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -154, Underdog Moneyline: +130)
• 8/30/2025: 4-2 STL (Favorite: Reds, Spread: -1.5, Total: 8, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 8/29/2025: 7-5 STL (Favorite: Reds, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)
• 6/22/2025: 4-1 CIN (Favorite: Reds, Spread: -1.5, Total: 9.5, Favorite Moneyline: -112, Underdog Moneyline: -104)
• 6/21/2025: 6-5 STL (Favorite: Cardinals, Spread: -1.5, Total: 9, Favorite Moneyline: -198, Underdog Moneyline: +166)
• 6/20/2025: 6-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 8.5, Favorite Moneyline: -142, Underdog Moneyline: +120)

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