Red Sox vs Cardinals Prediction, Odds, Moneyline, Spread & Over/Under for April 12

Odds updated as of 10:12 p.m.

Sunday's slate in the MLB includes a matchup between the Boston Red Sox and the St. Louis Cardinals.

Before you do any MLB betting on this game at FanDuel Sportsbook, here's everything you need to know.

Red Sox vs Cardinals Game Info

• Boston Red Sox (4-9) vs. St. Louis Cardinals (8-5)
• Date: Sunday, April 12, 2026
• Time: 2:15 p.m. ET
• Venue: Busch Stadium -- St. Louis, Missouri
• Coverage: Cardinals.TV and NESN

Red Sox vs Cardinals Odds & Moneyline

• All MLB odds, betting lines and prop bets are available on FanDuel Sportsbook.
• Moneyline: BOS: (-122) | STL: (+104)
• Spread: BOS: -1.5 (+138) | STL: +1.5 (-166)
• Total: 8.5 -- Over: (-118) | Under: (-104)

Red Sox vs Cardinals Probable Starting Pitchers

Probable Pitchers: Brayan Bello (Red Sox) - 0-1, 9.00 ERA vs Andre Pallante (Cardinals) - 1-0, 1.80 ERA

The Red Sox will give the ball to Brayan Bello (0-1, 9.00 ERA), who is eyeing win No. 1 on the season, and the Cardinals will counter with Andre Pallante (1-0, 1.80 ERA). Bello has a record of 0-2-0 ATS in two starts with a spread this season. Bello has yet to start a game this season when his team was the moneyline favorite. Pallante has started two games with set spreads, and the Cardinals went 1-1-0. The Cardinals were named the moneyline underdog for one Pallante start this season -- they won.

Red Sox vs Cardinals Prediction & Pick

All MLB win probability predictions and picks are according to numberFire.
Prediction: Cardinals win (51.1%)

Red Sox vs Cardinals Moneyline

• St. Louis is the underdog, +104 on the moneyline, while Boston is a -122 favorite despite being on the road.

Red Sox vs Cardinals Spread

• The Cardinals are hosting the Red Sox, and are +1.5 on the runline. The Cardinals are +138 to cover the spread, and the Red Sox are -166.

Red Sox vs Cardinals Over/Under

• The over/under for the Red Sox versus Cardinals contest on April 12 has been set at 8.5, with -118 odds on the over and -104 odds on the under.

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Red Sox vs Cardinals Betting Trends

• The Red Sox have been favorites in 11 games this season and have come away with the win four times (36.4%) in those contests.
• This season Boston has been victorious four times in 11 chances when named as a favorite of at least -122 on the moneyline.
• Contests with the Red Sox have gone over the total set by sportsbooks in six of 13 chances this season.
• The Red Sox have an against the spread mark of 3-10-0 in 13 games with a line this season.
• The Cardinals have won seven of the 11 games they were the underdog on the moneyline this season (63.6%).
• St. Louis is 5-3 (winning 62.5% of its games) when playing as a moneyline underdog of +104 or longer.
• The Cardinals have played in 13 games with a set over/under, and have combined with their opponents to go over the total six times (6-6-1).
• The Cardinals have collected a 7-6-0 record against the spread this season (covering 53.8% of the time).

Red Sox Player Leaders

• Wilyer Abreu has 20 hits and an OBP of .415 to go with a slugging percentage of .686. All three of those stats are tops among Boston hitters this season. He has a .392 batting average, as well.
• He is second in batting average, 14th in on-base percentage, and fourth in slugging among all qualified hitters in MLB.
• Abreu will look for his third straight game with a hit in this matchup. In his last five games he is batting .400 with a double, a triple, a walk and three RBIs.
• Willson Contreras has a double, two home runs and 11 walks. He's batting .227 and slugging .386 with an on-base percentage of .404.
• Among all qualifying batters, he is 99th in batting average, 21st in on-base percentage and 86th in slugging percentage.
• Ceddanne Rafaela has 12 hits this season and has a slash line of .324/.375/.432.
• Rafaela brings a six-game hitting streak into this game. In his last 10 games he is hitting .321 with a double, a home run, two walks and three RBIs.
• Masataka Yoshida is batting .263 with a .500 OBP and three RBI for Boston this season.
• Yoshida brings a three-game hitting streak into this matchup. During his last five outings he is batting .357 with two doubles, three walks and three RBIs.

Cardinals Player Leaders

• Jordan Walker has accumulated 15 hits with a .667 slugging percentage, both team-best stats for the Cardinals. He's batting .313 and with an on-base percentage of .377.
• Including all qualifying hitters in MLB, he is 28th in batting average, 40th in on-base percentage and fifth in slugging percentage.
• Walker enters this matchup on a six-game hitting streak. During his last 10 games he is batting .289 with four home runs, three walks and nine RBIs.
• Alec Burleson has two doubles, a home run and 10 walks while hitting .245. He's slugging .347 with an on-base percentage of .367.
• His batting average ranks 83rd among all qualified players, his on-base percentage ranks 51st, and he is 106th in slugging.
• JJ Wetherholt has a double, a home run and 10 walks while batting .229.
• Ivan Herrera's .393 OBP paces his team.

Red Sox vs Cardinals Head to Head

• 4/10/2026: 3-2 STL (Favorite: Red Sox, Spread: -1.5, Total: 7.5, Favorite Moneyline: -136, Underdog Moneyline: +116)
• 4/6/2025: 18-7 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -122, Underdog Moneyline: +104)
• 4/6/2025: 5-4 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 4/4/2025: 13-9 BOS (Favorite: Red Sox, Spread: -1.5, Total: 9.5, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/19/2024: 11-3 BOS (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -130, Underdog Moneyline: +110)
• 5/18/2024: 7-2 STL (Favorite: Red Sox, Spread: -1.5, Total: 8.5, Favorite Moneyline: -118, Underdog Moneyline: -100)
• 5/17/2024: 10-6 STL (Favorite: Cardinals, Spread: -1.5, Total: 8, Favorite Moneyline: -108, Underdog Moneyline: -108)
• 5/14/2023: 9-1 STL (Favorite: Cardinals, Spread: -1.5, Total: 10, Favorite Moneyline: -120, Underdog Moneyline: +102)
• 5/13/2023: 4-3 STL (Favorite: Red Sox, Spread: -1.5, Total: 10.5, Favorite Moneyline: -134, Underdog Moneyline: +116)
• 5/12/2023: 8-6 STL (Favorite: Red Sox, Spread: -1.5, Total: 11, Favorite Moneyline: -112, Underdog Moneyline: -104)

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