Purdue vs Indiana College Basketball Prediction, Odds, Picks, Best Bets for Feb. 20

Big Ten play on Friday will see the the No. 7 Purdue Boilermakers (21-5, 11-4 Big Ten) host the Indiana Hoosiers (17-9, 8-7 Big Ten) at Mackey Arena, beginning at 8 p.m. ET.

Before you place your bet on this game at FanDuel Sportsbook, here are the NCAA basketball odds and spreads you need to know.

Purdue vs. Indiana Game Info and Odds

• Game day: Friday, February 20, 2026
• Game time: 8 p.m. ET
• TV channel: FOX
• Location: West Lafayette, Indiana
• Arena: Mackey Arena

Purdue vs. Indiana Picks and Prediction

All college basketball win probability predictions and picks are according to numberFire.
Prediction: Purdue win (82.4%)

Take a look at some betting insights for Purdue (-11.5) versus Indiana on Friday. The total has been set at 149.5 points for this game.

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Purdue vs. Indiana: ATS Betting Stats and Trends

• Purdue has won 12 games against the spread this season, while failing to cover 14 times.
• Indiana has put together a 13-13-0 ATS record so far this season.
• Purdue covers the spread when it is an 11.5-point favorite or more 46.2% of the time. That's less often than Indiana covers as an underdog of 11.5 or more (100%).
• Against the spread, the Boilermakers have fared worse at home, covering four times in 14 home games, and six times in nine road games.
• The Hoosiers' winning percentage against the spread at home is .533 (8-7-0). Away, it is .444 (4-5-0).
• Purdue has beaten the spread six times in 15 conference games.
• Indiana's Big Ten record against the spread is 8-7-0.

Purdue vs. Indiana: Moneyline Betting Stats

• Purdue has won in 16, or 80%, of the 20 contests it has been named as the moneyline favorite in this year.
• The Boilermakers have not lost in 10 games this year when favored by -800 or better on the moneyline.
• Indiana has compiled a 2-5 record in games it was the underdog on the moneyline (winning 28.6% of those games).
• The Hoosiers have played as a moneyline underdog of +530 or longer in just one game this season, which they lost.
• Purdue has an implied victory probability of 88.9% according to the moneyline set by oddsmakers for this matchup.

Purdue vs. Indiana Head-to-Head Comparison

• Purdue is outscoring opponents by 13.0 points per game with a +340 scoring differential overall. It puts up 82.5 points per game (55th in college basketball) and gives up 69.5 per contest (72nd in college basketball).
• Purdue's leading scorer, Braden Smith, is 300th in the nation putting up 14.9 points per game.
• Indiana puts up 80.3 points per game (93rd in college basketball) while giving up 71.3 per contest (111th in college basketball). It has a +234 scoring differential and outscores opponents by 9.0 points per game.
• Indiana's leading scorer, Lamar Wilkerson, is 15th in the nation, scoring 21.2 points per game.
• The Boilermakers win the rebound battle by 7.0 boards on average. They collect 34.3 rebounds per game, which ranks 74th in college basketball, while their opponents grab 27.3 per contest.
• Trey Kaufman-Renn paces the team with 9.1 rebounds per game (33rd in college basketball action).
• The 30.4 rebounds per game the Hoosiers accumulate rank 275th in the nation. Their opponents record 30.0.
• Tucker DeVries tops the team with 5.3 rebounds per game (476th in college basketball).
• Purdue scores 109.0 points per 100 possessions (12th in college basketball), while allowing 91.7 points per 100 possessions (100th in college basketball).
• The Hoosiers put up 105.7 points per 100 possessions (31st in college basketball), while allowing 93.8 points per 100 possessions (150th in college basketball).

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